276288

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 4775199..4775763 Replicon chromosome
Accession NZ_CP121355
Organism Mesorhizobium sp. WSM4906

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag QAZ22_RS22995 Protein ID WP_278202991.1
Coordinates 4775506..4775763 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag QAZ22_RS22990 Protein ID WP_278202990.1
Coordinates 4775199..4775519 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ22_RS22955 (QAZ22_22955) 4770234..4771109 + 876 WP_278207913.1 zinc ABC transporter permease AztB -
QAZ22_RS22960 (QAZ22_22960) 4771139..4772080 + 942 WP_278202986.1 zinc ABC transporter substrate-binding protein AztC -
QAZ22_RS22965 (QAZ22_22965) 4772227..4772565 + 339 WP_278207914.1 TIGR01244 family sulfur transferase -
QAZ22_RS22970 (QAZ22_22970) 4772798..4773265 - 468 WP_059187534.1 Lrp/AsnC family transcriptional regulator -
QAZ22_RS22975 (QAZ22_22975) 4773404..4774519 + 1116 WP_278202987.1 4-hydroxyphenylpyruvate dioxygenase -
QAZ22_RS22980 (QAZ22_22980) 4774589..4774813 + 225 WP_278202988.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
QAZ22_RS22985 (QAZ22_22985) 4774810..4775187 + 378 WP_278202989.1 type II toxin-antitoxin system VapC family toxin -
QAZ22_RS22990 (QAZ22_22990) 4775199..4775519 - 321 WP_278202990.1 BrnA antitoxin family protein Antitoxin
QAZ22_RS22995 (QAZ22_22995) 4775506..4775763 - 258 WP_278202991.1 BrnT family toxin Toxin
QAZ22_RS23000 (QAZ22_23000) 4775840..4776376 - 537 WP_278202992.1 DinB family protein -
QAZ22_RS23005 (QAZ22_23005) 4776381..4777406 - 1026 WP_278202993.1 fumarylacetoacetate hydrolase family protein -
QAZ22_RS23010 (QAZ22_23010) 4777403..4778305 - 903 WP_278202994.1 MBL fold metallo-hydrolase -
QAZ22_RS23015 (QAZ22_23015) 4778302..4779615 - 1314 WP_278202995.1 homogentisate 1,2-dioxygenase -
QAZ22_RS23020 (QAZ22_23020) 4779748..4780218 + 471 WP_278202996.1 MarR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(31-104)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9346.93 Da        Isoelectric Point: 10.1808

>T276288 WP_278202991.1 NZ_CP121355:c4775763-4775506 [Mesorhizobium sp. WSM4906]
MKIVWDEPKRLANIDKHGLDFAALDEEFFLASTIRAAKAGRFMAIGWIVGGVVAVVFARLGSEGISIISMRPANQAERRL
FDGKV

Download         Length: 258 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12114.65 Da        Isoelectric Point: 10.4726

>AT276288 WP_278202990.1 NZ_CP121355:c4775519-4775199 [Mesorhizobium sp. WSM4906]
MAKSKLRIKKPDKEFESGKGFTREDWDAVSDNPEWTEEDFRNARPFAEVFPDLADSIRRSRGRPALDNPKKQVTLRLDSD
VIARFRAGGPGWQSRINDILRKAAGL

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References