276285

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2864411..2865063 Replicon chromosome
Accession NZ_CP121355
Organism Mesorhizobium sp. WSM4906

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QAZ22_RS13680 Protein ID WP_278207290.1
Coordinates 2864411..2864800 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QAZ22_RS13685 Protein ID WP_278207291.1
Coordinates 2864797..2865063 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ22_RS13650 (QAZ22_13650) 2859652..2859909 - 258 WP_278207284.1 hypothetical protein -
QAZ22_RS13655 (QAZ22_13655) 2859938..2860576 - 639 WP_278207285.1 FMN-dependent NADH-azoreductase -
QAZ22_RS13660 (QAZ22_13660) 2860688..2861635 + 948 WP_278207286.1 LysR family transcriptional regulator -
QAZ22_RS13665 (QAZ22_13665) 2861767..2862711 - 945 WP_278207287.1 trypsin-like peptidase domain-containing protein -
QAZ22_RS13670 (QAZ22_13670) 2862881..2863756 + 876 WP_278207288.1 S1C family serine protease -
QAZ22_RS13675 (QAZ22_13675) 2863786..2864406 + 621 WP_278207289.1 helix-turn-helix transcriptional regulator -
QAZ22_RS13680 (QAZ22_13680) 2864411..2864800 - 390 WP_278207290.1 type II toxin-antitoxin system VapC family toxin Toxin
QAZ22_RS13685 (QAZ22_13685) 2864797..2865063 - 267 WP_278207291.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QAZ22_RS13690 (QAZ22_13690) 2865222..2866088 + 867 WP_278207292.1 NAD(P)-dependent oxidoreductase -
QAZ22_RS13695 (QAZ22_13695) 2866226..2866741 - 516 WP_278207293.1 TIGR00645 family protein -
QAZ22_RS13700 (QAZ22_13700) 2867041..2869332 - 2292 WP_278207294.1 OmpA family protein -
QAZ22_RS13705 (QAZ22_13705) 2869490..2869936 + 447 WP_278207295.1 YcgN family cysteine cluster protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-86)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13925.05 Da        Isoelectric Point: 5.1392

>T276285 WP_278207290.1 NZ_CP121355:c2864800-2864411 [Mesorhizobium sp. WSM4906]
VIIDSSALVAILRAEPGHDRLVQAIADAARRLIAAPTLLETSMVLAGGWQDEILDRLDALLRTASIETVAFTADHAAVAR
QAFLRYGKGRHPAALNFGDCIAYATARLEAMPLLFKGDDFRLTDIEPAI

Download         Length: 390 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10192.56 Da        Isoelectric Point: 7.0198

>AT276285 WP_278207291.1 NZ_CP121355:c2865063-2864797 [Mesorhizobium sp. WSM4906]
MALSIKNMEVERLARELARRRRISVTEAIRQSLEREVARERLVPRNENSDLFQRLMAISDSAAQVPKRENAMTEDEILGY
DEHGAPTR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References