Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 5485726..5486528 Replicon chromosome
Accession NZ_CP121354
Organism Mesorhizobium sp. WSM4904

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag QAZ47_RS26675 Protein ID WP_278231346.1
Coordinates 5486001..5486528 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag QAZ47_RS26670 Protein ID WP_278203757.1
Coordinates 5485726..5486004 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ47_RS26655 (QAZ47_26655) 5481653..5482117 + 465 WP_278231343.1 NUDIX domain-containing protein -
QAZ47_RS26660 (QAZ47_26660) 5482126..5482878 - 753 WP_278231344.1 DNA repair protein RecO -
QAZ47_RS26665 (QAZ47_26665) 5483009..5485564 + 2556 WP_278231345.1 mechanosensitive ion channel -
QAZ47_RS26670 (QAZ47_26670) 5485726..5486004 + 279 WP_278203757.1 DUF1778 domain-containing protein Antitoxin
QAZ47_RS26675 (QAZ47_26675) 5486001..5486528 + 528 WP_278231346.1 GNAT family N-acetyltransferase Toxin
QAZ47_RS26680 (QAZ47_26680) 5486535..5487428 - 894 WP_278231347.1 aminoglycoside phosphotransferase family protein -
QAZ47_RS26685 (QAZ47_26685) 5487531..5488463 - 933 WP_278231349.1 GTPase Era -
QAZ47_RS26690 (QAZ47_26690) 5488448..5489164 - 717 WP_278077900.1 ribonuclease III -
QAZ47_RS26695 (QAZ47_26695) 5489169..5489918 - 750 WP_278077899.1 signal peptidase I -
QAZ47_RS26700 (QAZ47_26700) 5489999..5490412 - 414 WP_278077898.1 holo-ACP synthase -
QAZ47_RS26705 (QAZ47_26705) 5490409..5490996 - 588 WP_278231350.1 DUF2062 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18910.58 Da        Isoelectric Point: 8.2863

>T276282 WP_278231346.1 NZ_CP121354:5486001-5486528 [Mesorhizobium sp. WSM4904]
MTLPRWREEPISKSHDRASFDCGDEQMNDFLRRFARQSHEQNASKTFCAVDNANPDRVLGFYTIAPSAVAHEQVPAALTK
GLARHEVSGFKLARLATDLSVAGQGLGGQLLAAAALRCLRVAGEGGGLLFIIDAKSERAANWYRGYGAEPLSGKPLTLVM
PLATFAADLRAKDLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10330.11 Da        Isoelectric Point: 10.2441

>AT276282 WP_278203757.1 NZ_CP121354:5485726-5486004 [Mesorhizobium sp. WSM4904]
MSKPASDRTERFNIRIRPAQKAMIARAAALSHKDMTDFILDKVLPEAEAVIKAIEKTEVSERDFKRILELLEHPPKPNAK
LRAAIAALPDTI

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References