Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 5306445..5307118 Replicon chromosome
Accession NZ_CP121354
Organism Mesorhizobium sp. WSM4904

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QAZ47_RS25710 Protein ID WP_278231217.1
Coordinates 5306445..5306867 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QAZ47_RS25715 Protein ID WP_278231218.1
Coordinates 5306864..5307118 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ47_RS25665 (QAZ47_25665) 5301691..5301969 - 279 WP_278203524.1 type II toxin-antitoxin system RelE/ParE family toxin -
QAZ47_RS25675 (QAZ47_25675) 5302209..5302514 - 306 WP_126084876.1 ETC complex I subunit -
QAZ47_RS25680 (QAZ47_25680) 5302830..5303810 + 981 WP_278231212.1 NAD(P)H-dependent oxidoreductase -
QAZ47_RS25685 (QAZ47_25685) 5304048..5305217 + 1170 WP_278231213.1 NAD(P)/FAD-dependent oxidoreductase -
QAZ47_RS25695 (QAZ47_25695) 5305436..5305573 + 138 WP_278203527.1 hypothetical protein -
QAZ47_RS25700 (QAZ47_25700) 5305584..5305967 - 384 WP_278231214.1 type II toxin-antitoxin system VapC family toxin -
QAZ47_RS25705 (QAZ47_25705) 5305964..5306221 - 258 WP_278231215.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
QAZ47_RS25710 (QAZ47_25710) 5306445..5306867 - 423 WP_278231217.1 type II toxin-antitoxin system VapC family toxin Toxin
QAZ47_RS25715 (QAZ47_25715) 5306864..5307118 - 255 WP_278231218.1 Arc family DNA-binding protein Antitoxin
QAZ47_RS25720 (QAZ47_25720) 5307194..5307898 - 705 WP_278203532.1 DnaA regulatory inactivator HdaA -
QAZ47_RS25725 (QAZ47_25725) 5307900..5309078 - 1179 WP_278203533.1 AI-2E family transporter -
QAZ47_RS25730 (QAZ47_25730) 5309050..5309607 - 558 WP_278231219.1 CDP-alcohol phosphatidyltransferase family protein -
QAZ47_RS25735 (QAZ47_25735) 5309905..5310984 + 1080 WP_278231220.1 phosphoribosylformylglycinamidine cyclo-ligase -
QAZ47_RS25740 (QAZ47_25740) 5310981..5311688 + 708 WP_278231221.1 phosphoribosylglycinamide formyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin

Arc-like DNA binding domain

(9-46)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14898.27 Da        Isoelectric Point: 5.6981

>T276281 WP_278231217.1 NZ_CP121354:c5306867-5306445 [Mesorhizobium sp. WSM4904]
MILLDTNVVSEMMRAEPHPAVLAWLDNQAAETLYLSSVTLAEILFGIEAMPAGRRKSALAEVFSGIFAVFDQRILVLDVE
AARRYAGLAVKARAAGKGFPVPDGYIAAIAAAKCFQVASRDTAPFHAAGVPVINPWDNAA

Download         Length: 423 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9202.47 Da        Isoelectric Point: 7.0178

>AT276281 WP_278231218.1 NZ_CP121354:c5307118-5306864 [Mesorhizobium sp. WSM4904]
MTAVTIRNLPEETHRALRVRAAINGRSTEGEIRAILEDAVRPEGRVKLGSLLSDIARRAGVKNEDVDALEQALGKRPAEP
LSFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References