Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2870315..2870967 Replicon chromosome
Accession NZ_CP121354
Organism Mesorhizobium sp. WSM4904

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QAZ47_RS13740 Protein ID WP_278233615.1
Coordinates 2870315..2870704 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QAZ47_RS13745 Protein ID WP_278207291.1
Coordinates 2870701..2870967 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ47_RS13710 (QAZ47_13710) 2865579..2865809 - 231 WP_278233610.1 hypothetical protein -
QAZ47_RS13715 (QAZ47_13715) 2865865..2866503 - 639 WP_278233611.1 FMN-dependent NADH-azoreductase -
QAZ47_RS13720 (QAZ47_13720) 2866615..2867562 + 948 WP_278233612.1 LysR family transcriptional regulator -
QAZ47_RS13725 (QAZ47_13725) 2867671..2868615 - 945 WP_278207287.1 trypsin-like peptidase domain-containing protein -
QAZ47_RS13730 (QAZ47_13730) 2868785..2869660 + 876 WP_278233613.1 S1C family serine protease -
QAZ47_RS13735 (QAZ47_13735) 2869690..2870310 + 621 WP_278233614.1 helix-turn-helix transcriptional regulator -
QAZ47_RS13740 (QAZ47_13740) 2870315..2870704 - 390 WP_278233615.1 type II toxin-antitoxin system VapC family toxin Toxin
QAZ47_RS13745 (QAZ47_13745) 2870701..2870967 - 267 WP_278207291.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QAZ47_RS13750 (QAZ47_13750) 2871126..2871992 + 867 WP_278233616.1 NAD(P)-dependent oxidoreductase -
QAZ47_RS13755 (QAZ47_13755) 2872130..2872645 - 516 WP_278207293.1 TIGR00645 family protein -
QAZ47_RS13760 (QAZ47_13760) 2873008..2875266 - 2259 WP_278233617.1 OmpA family protein -
QAZ47_RS13765 (QAZ47_13765) 2875461..2875907 + 447 WP_278233618.1 YcgN family cysteine cluster protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-86)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13928.98 Da        Isoelectric Point: 5.1392

>T276278 WP_278233615.1 NZ_CP121354:c2870704-2870315 [Mesorhizobium sp. WSM4904]
VIIDSSALVAILRAEPGHDRFVQAIADAARRLIAAPTLLETSTVLAGGWQDEILDRLDALLRTASIETVAFTADHAAVAR
QAFLRYGKGRHPAALNFGDCIAYATARLEAMPLLFKGDDFRLTDIEPAI

Download         Length: 390 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10192.56 Da        Isoelectric Point: 7.0198

>AT276278 WP_278207291.1 NZ_CP121354:c2870967-2870701 [Mesorhizobium sp. WSM4904]
MALSIKNMEVERLARELARRRRISVTEAIRQSLEREVARERLVPRNENSDLFQRLMAISDSAAQVPKRENAMTEDEILGY
DEHGAPTR

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References