Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2661159..2661787 Replicon chromosome
Accession NZ_CP121354
Organism Mesorhizobium sp. WSM4904

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QAZ47_RS12705 Protein ID WP_278233466.1
Coordinates 2661401..2661787 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QAZ47_RS12700 Protein ID WP_126098270.1
Coordinates 2661159..2661404 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ47_RS12675 (QAZ47_12675) 2656888..2657976 - 1089 WP_278233464.1 AbrB family transcriptional regulator -
QAZ47_RS12680 (QAZ47_12680) 2658045..2658356 - 312 WP_278207101.1 putative quinol monooxygenase -
QAZ47_RS12685 (QAZ47_12685) 2658496..2659281 - 786 WP_278207102.1 SDR family oxidoreductase -
QAZ47_RS12690 (QAZ47_12690) 2659353..2659787 - 435 WP_278233465.1 DsrE family protein -
QAZ47_RS12695 (QAZ47_12695) 2659997..2661079 + 1083 WP_278207104.1 hypothetical protein -
QAZ47_RS12700 (QAZ47_12700) 2661159..2661404 + 246 WP_126098270.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QAZ47_RS12705 (QAZ47_12705) 2661401..2661787 + 387 WP_278233466.1 type II toxin-antitoxin system VapC family toxin Toxin
QAZ47_RS12710 (QAZ47_12710) 2661790..2662737 - 948 WP_278207107.1 cation diffusion facilitator family transporter -
QAZ47_RS12715 (QAZ47_12715) 2662743..2664932 - 2190 WP_278233467.1 anthranilate synthase -
QAZ47_RS12720 (QAZ47_12720) 2665224..2666279 - 1056 WP_278233468.1 succinylglutamate desuccinylase/aspartoacylase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-121)

Antitoxin

SpoVT-AbrB domain

(7-45)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14273.41 Da        Isoelectric Point: 5.2060

>T276277 WP_278233466.1 NZ_CP121354:2661401-2661787 [Mesorhizobium sp. WSM4904]
VIYLLDTNAVIAVMKGDDDLLTVLKRNKPQDFALSAIVVHELYYGAYRGQRTEENLARLDALLFPVLEFDREDARHAGEI
RAMLATSGTPIGPFDVLIGGQARARGLTLMTRNVREFERIGGLAIETW

Download         Length: 387 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9442.64 Da        Isoelectric Point: 4.6558

>AT276277 WP_126098270.1 NZ_CP121354:2661159-2661404 [Mesorhizobium sp. WSM4904]
MNKAKIFWSGRSQAVRLPKEFRFETDEVSIRRHGQTVVLEPLPQDWAWLDQVIGTLDDDFVDAAEERVEEQKRPALGDVF
K

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References