276275

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 388826..389378 Replicon chromosome
Accession NZ_CP121354
Organism Mesorhizobium sp. WSM4904

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag QAZ47_RS01800 Protein ID WP_278233752.1
Coordinates 389124..389378 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID -
Locus tag QAZ47_RS01795 Protein ID WP_278232300.1
Coordinates 388826..389137 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAZ47_RS01770 (QAZ47_01770) 384847..385221 - 375 WP_278232296.1 hydroxyisourate hydrolase -
QAZ47_RS01775 (QAZ47_01775) 385416..386840 + 1425 WP_278232297.1 allantoinase PuuE -
QAZ47_RS01780 (QAZ47_01780) 386851..387714 + 864 WP_278205264.1 bifunctional allantoicase/(S)-ureidoglycine aminohydrolase -
QAZ47_RS01785 (QAZ47_01785) 387711..388202 + 492 WP_278232298.1 ureidoglycolate lyase -
QAZ47_RS01790 (QAZ47_01790) 388220..388813 + 594 WP_278232299.1 nucleoside deaminase -
QAZ47_RS01795 (QAZ47_01795) 388826..389137 - 312 WP_278232300.1 BrnA antitoxin family protein Antitoxin
QAZ47_RS01800 (QAZ47_01800) 389124..389378 - 255 WP_278233752.1 BrnT family toxin Toxin
QAZ47_RS01805 (QAZ47_01805) 389565..391550 + 1986 WP_278232301.1 CocE/NonD family hydrolase -
QAZ47_RS01810 (QAZ47_01810) 391700..393286 + 1587 WP_278232302.1 ABC transporter substrate-binding protein -
QAZ47_RS01815 (QAZ47_01815) 393303..394262 + 960 WP_278075125.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-77)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(28-100)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9506.07 Da        Isoelectric Point: 9.9216

>T276275 WP_278233752.1 NZ_CP121354:c389378-389124 [Mesorhizobium sp. WSM4904]
MKIVWDEPKRVTNLENRGLDFADLDLDFFATSIVLPAKAGRLMAIGEFRQTILAVIFKPLGSEAISVISMRRASRKERSA
YEHP

Download         Length: 255 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11505.13 Da        Isoelectric Point: 10.1371

>AT276275 WP_278232300.1 NZ_CP121354:c389137-388826 [Mesorhizobium sp. WSM4904]
MSTHKRRIRPLTDEDEAEIQKQIAADPDDAEATDEQLAQAAPFAKALPELFESIRRARGRPAAEKPKQIVSIRLDQDVIS
KFKATGKGWQARINEVLKKAKVG

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References