Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1183992..1184652 Replicon chromosome
Accession NZ_CP121298
Organism Salmonella enterica subsp. enterica strain KKP 3080

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag P1839_RS05730 Protein ID WP_000244756.1
Coordinates 1184239..1184652 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag P1839_RS05725 Protein ID WP_000351186.1
Coordinates 1183992..1184258 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1839_RS05705 (1179920) 1179920..1181353 - 1434 WP_278219240.1 6-phospho-beta-glucosidase BglA -
P1839_RS05710 (1181512) 1181512..1181823 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
P1839_RS05715 (1181987) 1181987..1182646 + 660 WP_000250289.1 hemolysin III family protein -
P1839_RS05720 (1182762) 1182762..1183742 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
P1839_RS05725 (1183992) 1183992..1184258 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
P1839_RS05730 (1184239) 1184239..1184652 + 414 WP_000244756.1 protein YgfX Toxin
P1839_RS05735 (1184705) 1184705..1185226 - 522 WP_001055885.1 flavodoxin FldB -
P1839_RS05740 (1185339) 1185339..1186235 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
P1839_RS05745 (1186259) 1186259..1186972 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P1839_RS05750 (1186978) 1186978..1188711 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T276254 WP_000244756.1 NZ_CP121298:1184239-1184652 [Salmonella enterica subsp. enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT276254 WP_000351186.1 NZ_CP121298:1183992-1184258 [Salmonella enterica subsp. enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References