Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2529188..2529331 Replicon chromosome
Accession NZ_CP121297
Organism Salmonella enterica subsp. enterica strain KKP 1762

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2529190..2529293 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2529188..2529331 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1N06_RS12400 2524587..2524715 - 129 Protein_2409 helix-turn-helix domain-containing protein -
P1N06_RS12405 2525205..2525975 + 771 WP_000758583.1 transporter substrate-binding domain-containing protein -
P1N06_RS12410 2525971..2526159 + 189 Protein_2411 tail fiber assembly protein -
P1N06_RS12415 2526411..2526596 + 186 WP_071787785.1 PagK family vesicle-borne virulence factor -
P1N06_RS12420 2526687..2526796 - 110 Protein_2413 tail fiber assembly protein -
P1N06_RS12425 2526845..2527177 - 333 WP_031607880.1 DUF1353 domain-containing protein -
P1N06_RS12430 2527283..2527816 - 534 Protein_2415 DUF4376 domain-containing protein -
P1N06_RS12435 2527770..2528126 - 357 WP_076737138.1 hypothetical protein -
P1N06_RS12440 2528217..2529059 + 843 Protein_2417 tyrosine-type recombinase/integrase -
- 2529188..2529331 + 144 - - Antitoxin
- 2529190..2529293 - 104 - - Toxin
P1N06_RS12445 2529432..2529785 - 354 WP_000722368.1 YebY family protein -
P1N06_RS12450 2529802..2530677 - 876 WP_076737139.1 copper homeostasis membrane protein CopD -
P1N06_RS12455 2530678..2531052 - 375 WP_000168393.1 CopC domain-containing protein YobA -
P1N06_RS12460 2531190..2531420 + 231 WP_000856224.1 DNA polymerase III subunit theta -
P1N06_RS12465 2531528..2532184 + 657 WP_023234150.1 carbon-nitrogen hydrolase family protein -
P1N06_RS12470 2532208..2532906 + 699 WP_000944285.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2484993..2534994 50001


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T276243 NZ_CP121297:c2529293-2529190 [Salmonella enterica subsp. enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT276243 NZ_CP121297:2529188-2529331 [Salmonella enterica subsp. enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References