Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 3374582..3375093 Replicon chromosome
Accession NZ_CP121274
Organism Microbacterium proteolyticum strain ustc

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag P8R59_RS16950 Protein ID WP_278102020.1
Coordinates 3374827..3375093 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag P8R59_RS16945 Protein ID WP_077051824.1
Coordinates 3374582..3374830 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8R59_RS16920 3369851..3371272 - 1422 WP_278102015.1 histidine kinase -
P8R59_RS16925 3371273..3371719 - 447 WP_278102016.1 hypothetical protein -
P8R59_RS16930 3371898..3372752 + 855 WP_278102017.1 hypothetical protein -
P8R59_RS16935 3372807..3374120 - 1314 WP_278102018.1 MFS transporter -
P8R59_RS16940 3374194..3374475 - 282 WP_278102019.1 hypothetical protein -
P8R59_RS16945 3374582..3374830 + 249 WP_077051824.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P8R59_RS16950 3374827..3375093 + 267 WP_278102020.1 Txe/YoeB family addiction module toxin Toxin
P8R59_RS16955 3375124..3376197 - 1074 WP_278102021.1 redox-regulated ATPase YchF -
P8R59_RS16960 3376237..3376986 - 750 WP_278102022.1 class I SAM-dependent methyltransferase -
P8R59_RS16965 3377161..3377757 + 597 WP_278102023.1 3'-5' exonuclease -
P8R59_RS16970 3377808..3379130 + 1323 WP_278102024.1 DNA recombination protein RmuC -
P8R59_RS16975 3379141..3379350 - 210 WP_077051830.1 UDP-N-acetylmuramyl pentapeptide phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-70)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10342.64 Da        Isoelectric Point: 6.2173

>T276177 WP_278102020.1 NZ_CP121274:3374827-3375093 [Microbacterium proteolyticum]
VSQLSLAWTAEGWEDYLYWQTQDRKTLRRINQLIADMLRDDPFEGIGKPEPLRHALAGALSRRIDEANRLVYITDDTHVT
VLQARYHY

Download         Length: 267 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9252.35 Da        Isoelectric Point: 4.5098

>AT276177 WP_077051824.1 NZ_CP121274:3374582-3374830 [Microbacterium proteolyticum]
MAITTSEARRDLFGLIERVNLDHTEIEITSKRGSAVLMSKDEYDSLVETSYLLRSPENARRLLSALDSARSGDVQERDLI
EP

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References