276176

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 89163..89716 Replicon chromosome
Accession NZ_CP121274
Organism Microbacterium proteolyticum strain ustc

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P8R59_RS01195 Protein ID WP_278102367.1
Coordinates 89163..89435 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P8R59_RS01200 Protein ID WP_278102368.1
Coordinates 89432..89716 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8R59_RS01175 84172..85218 + 1047 WP_077052190.1 MoxR family ATPase -
P8R59_RS01180 85226..86473 + 1248 WP_278102364.1 DUF58 domain-containing protein -
P8R59_RS01185 86460..88766 + 2307 WP_278102365.1 DUF3488 and transglutaminase-like domain-containing protein -
P8R59_RS01190 88780..89088 - 309 WP_278102366.1 hypothetical protein -
P8R59_RS01195 89163..89435 - 273 WP_278102367.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8R59_RS01200 89432..89716 - 285 WP_278102368.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P8R59_RS01210 89895..90863 - 969 WP_278102369.1 acetamidase/formamidase family protein -
P8R59_RS01215 90860..92284 - 1425 WP_278102370.1 APC family permease -
P8R59_RS01220 92340..93230 - 891 WP_278102371.1 proline iminopeptidase-family hydrolase -
P8R59_RS01225 93312..94052 + 741 WP_278102372.1 GntR family transcriptional regulator -
P8R59_RS01230 94055..94630 - 576 WP_278102373.1 GNAT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10465.13 Da        Isoelectric Point: 10.3955

>T276176 WP_278102367.1 NZ_CP121274:c89435-89163 [Microbacterium proteolyticum]
MTDGYEVVFTRTARRALAQELPEKIAAAAFEFILGALRENPRRVGKPLREPLAPLYSARRGEYRVLYRIVDERLVIEVVS
VVHRRDAYHR

Download         Length: 273 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10052.21 Da        Isoelectric Point: 4.3952

>AT276176 WP_278102368.1 NZ_CP121274:c89716-89432 [Microbacterium proteolyticum]
MTTLSLADARANLSKLVESAVSTHERFEVTRNGDRAAVLLSADDYDSLLETVDVLSRPDEVDAIRRGLADLEAGEMFSAA
EVRAAMAARGRATA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References