276174

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2865361..2865923 Replicon chromosome
Accession NZ_CP121270
Organism Gordonia hongkongensis strain RL-LY01

Toxin (Protein)


Gene name relE Uniprot ID A0A6G7W718
Locus tag P9A14_RS13090 Protein ID WP_055477308.1
Coordinates 2865361..2865651 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6G7W6R5
Locus tag P9A14_RS13095 Protein ID WP_055477309.1
Coordinates 2865648..2865923 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9A14_RS13070 (P9A14_13070) 2861312..2863372 + 2061 WP_068970440.1 DEAD/DEAH box helicase family protein -
P9A14_RS13075 (P9A14_13075) 2863407..2863646 + 240 WP_055477305.1 hypothetical protein -
P9A14_RS13080 (P9A14_13080) 2864235..2864468 + 234 WP_055477307.1 hypothetical protein -
P9A14_RS13085 (P9A14_13085) 2865136..2865342 + 207 WP_055477311.1 hypothetical protein -
P9A14_RS13090 (P9A14_13090) 2865361..2865651 - 291 WP_055477308.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9A14_RS13095 (P9A14_13095) 2865648..2865923 - 276 WP_055477309.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
P9A14_RS13100 (P9A14_13100) 2866043..2866519 - 477 WP_254661286.1 TetR family transcriptional regulator -
P9A14_RS13105 (P9A14_13105) 2866532..2866663 - 132 Protein_2581 hypothetical protein -
P9A14_RS13110 (P9A14_13110) 2866660..2867187 - 528 WP_065631669.1 GNAT family N-acetyltransferase -
P9A14_RS13115 (P9A14_13115) 2867595..2868356 + 762 WP_068970441.1 hypothetical protein -
P9A14_RS13120 (P9A14_13120) 2868411..2868716 + 306 WP_068970442.1 hypothetical protein -
P9A14_RS13125 (P9A14_13125) 2868768..2869148 - 381 WP_065631666.1 SRPBCC family protein -
P9A14_RS13130 (P9A14_13130) 2869297..2870202 - 906 WP_065631665.1 RNA polymerase sigma-70 factor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10938.40 Da        Isoelectric Point: 9.7360

>T276174 WP_055477308.1 NZ_CP121270:c2865651-2865361 [Gordonia hongkongensis]
MSDAPTDSSAPYRVEVASPARRDLQRLPSRIVHAVIEFISGPLAENPHRLSKPLRDDLADLHSARRGDYRILLRIDDPNH
TIVIVRIDHRAHAYRT

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9718.86 Da        Isoelectric Point: 4.3809

>AT276174 WP_055477309.1 NZ_CP121270:c2865923-2865648 [Gordonia hongkongensis]
MTTVPLGEAKDKLSALVDSAESTHDIITITKHGKPAAVLMSADDLESLHETIYWLSRAGVRDDVATADAEYAAGETVSID
DLRAEHGMPPK

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6G7W718

Antitoxin

Source ID Structure
AlphaFold DB A0A6G7W6R5

References