276173

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 1207956..1208629 Replicon chromosome
Accession NZ_CP121270
Organism Gordonia hongkongensis strain RL-LY01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P9A14_RS05510 Protein ID WP_137810536.1
Coordinates 1208225..1208629 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P9A14_RS05505 Protein ID WP_137810537.1
Coordinates 1207956..1208228 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9A14_RS05490 (P9A14_05490) 1203380..1204363 + 984 WP_165630431.1 LLM class F420-dependent oxidoreductase -
P9A14_RS05495 (P9A14_05495) 1204880..1206046 - 1167 WP_137810539.1 pyridoxal phosphate-dependent aminotransferase -
P9A14_RS05500 (P9A14_05500) 1206144..1207823 + 1680 WP_137810538.1 serine/threonine-protein kinase -
P9A14_RS05505 (P9A14_05505) 1207956..1208228 + 273 WP_137810537.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P9A14_RS05510 (P9A14_05510) 1208225..1208629 + 405 WP_137810536.1 type II toxin-antitoxin system VapC family toxin Toxin
P9A14_RS05515 (P9A14_05515) 1208631..1210307 - 1677 WP_065631752.1 DEAD/DEAH box helicase -
P9A14_RS05520 (P9A14_05520) 1210374..1211303 - 930 WP_137810535.1 oxygenase MpaB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-46)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14167.42 Da        Isoelectric Point: 4.6533

>T276173 WP_137810536.1 NZ_CP121270:1208225-1208629 [Gordonia hongkongensis]
MIYLDTSAMVKLVVREAETAPLIEWFALRPGVPTVTSALGRVELMRTALRDGSPGLHERARDLLDALDVIPLSAAVIDIA
ESIGPSSLRSLDALHLASATVIRAEMTAFVAYDQRLTAGASALGYPVVAPGAEL

Download         Length: 405 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9823.27 Da        Isoelectric Point: 11.0590

>AT276173 WP_137810537.1 NZ_CP121270:1207956-1208228 [Gordonia hongkongensis]
MRTIGIRELRQHASRYLAQVEAGEELAITNRGRTVARLVPVSAGERSREALIEAGILVPARSAGGITGLHPETLPTRALT
KVLDQVREDR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References