Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3786941..3787598 Replicon chromosome
Accession NZ_CP121269
Organism Enterobacter hormaechei subsp. xiangfangensis strain F81Y

Toxin (Protein)


Gene name cptA Uniprot ID A0A7T9SH06
Locus tag P9J39_RS17975 Protein ID WP_023295382.1
Coordinates 3786941..3787351 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag P9J39_RS17980 Protein ID WP_003863437.1
Coordinates 3787332..3787598 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J39_RS17955 (P9J39_17955) 3782939..3784672 - 1734 WP_017382886.1 single-stranded-DNA-specific exonuclease RecJ -
P9J39_RS17960 (P9J39_17960) 3784678..3785391 - 714 WP_015571792.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P9J39_RS17965 (P9J39_17965) 3785420..3786316 - 897 WP_003863442.1 site-specific tyrosine recombinase XerD -
P9J39_RS17970 (P9J39_17970) 3786418..3786939 + 522 WP_015571793.1 flavodoxin FldB -
P9J39_RS17975 (P9J39_17975) 3786941..3787351 - 411 WP_023295382.1 protein YgfX Toxin
P9J39_RS17980 (P9J39_17980) 3787332..3787598 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
P9J39_RS17985 (P9J39_17985) 3787893..3788873 + 981 WP_039269839.1 tRNA-modifying protein YgfZ -
P9J39_RS17990 (P9J39_17990) 3788985..3789644 - 660 WP_003863433.1 hemolysin III family protein -
P9J39_RS17995 (P9J39_17995) 3789911..3790639 + 729 WP_039269836.1 MurR/RpiR family transcriptional regulator -
P9J39_RS18000 (P9J39_18000) 3790759..3792192 + 1434 WP_017382891.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16291.18 Da        Isoelectric Point: 11.4775

>T276170 WP_023295382.1 NZ_CP121269:c3787351-3786941 [Enterobacter hormaechei subsp. xiangfangensis]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGAPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT276170 WP_003863437.1 NZ_CP121269:c3787598-3787332 [Enterobacter hormaechei subsp. xiangfangensis]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T9SH06

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References