Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 623531..624107 Replicon chromosome
Accession NZ_CP121269
Organism Enterobacter hormaechei subsp. xiangfangensis strain F81Y

Toxin (Protein)


Gene name shpA Uniprot ID A0A800YKM1
Locus tag P9J39_RS02985 Protein ID WP_015572580.1
Coordinates 623531..623818 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID A0A801DSF4
Locus tag P9J39_RS02990 Protein ID WP_017694570.1
Coordinates 623805..624107 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9J39_RS02960 (P9J39_02960) 618648..619343 + 696 WP_045348386.1 winged helix-turn-helix domain-containing protein -
P9J39_RS02965 (P9J39_02965) 619493..619963 + 471 WP_023303035.1 MarR family transcriptional regulator -
P9J39_RS02970 (P9J39_02970) 619960..621027 + 1068 WP_026080654.1 HlyD family secretion protein -
P9J39_RS02975 (P9J39_02975) 621017..622093 + 1077 WP_015572578.1 DUF2955 domain-containing protein -
P9J39_RS02980 (P9J39_02980) 622090..623361 - 1272 WP_015572579.1 DUF445 domain-containing protein -
P9J39_RS02985 (P9J39_02985) 623531..623818 + 288 WP_015572580.1 BrnT family toxin Toxin
P9J39_RS02990 (P9J39_02990) 623805..624107 + 303 WP_017694570.1 BrnA antitoxin family protein Antitoxin
P9J39_RS02995 (P9J39_02995) 624136..624774 - 639 WP_032647144.1 LysE family translocator -
P9J39_RS03000 (P9J39_03000) 624813..625565 - 753 WP_015572582.1 AraC family transcriptional regulator -
P9J39_RS03005 (P9J39_03005) 625719..627089 + 1371 WP_278108353.1 NAD-dependent succinate-semialdehyde dehydrogenase -
P9J39_RS03010 (P9J39_03010) 627267..627812 - 546 WP_033486712.1 YfaZ family outer membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(32-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11296.81 Da        Isoelectric Point: 7.3587

>T276160 WP_015572580.1 NZ_CP121269:623531-623818 [Enterobacter hormaechei subsp. xiangfangensis]
MPIEYEWDSNKAKSNLQKHAIRFEDAVLVFDDPCHLSVQDRYENGEFRWQTIGLVQGVIVILVAHTVRFESGDEIIRIIS
ARKADRKERRRYEHR

Download         Length: 288 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11482.13 Da        Isoelectric Point: 10.4094

>AT276160 WP_017694570.1 NZ_CP121269:623805-624107 [Enterobacter hormaechei subsp. xiangfangensis]
MSIVKHKRGSAPEVSARREAELKALADKPDREIDYSDIPATEDDRWAGAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References