Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3349951..3350478 Replicon chromosome
Accession NZ_CP121261
Organism Achromobacter spanius strain LIG8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P8T11_RS14885 Protein ID WP_268081220.1
Coordinates 3349951..3350226 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P8T11_RS14890 Protein ID WP_268081219.1
Coordinates 3350260..3350478 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T11_RS14865 (P8T11_14865) 3345535..3346560 - 1026 WP_268081222.1 tripartite tricarboxylate transporter substrate binding protein -
P8T11_RS14870 (P8T11_14870) 3346509..3347573 - 1065 WP_268081221.1 NADPH:quinone oxidoreductase family protein -
P8T11_RS14875 (P8T11_14875) 3347573..3348739 - 1167 WP_268082351.1 CoA transferase -
P8T11_RS14880 (P8T11_14880) 3348935..3349924 + 990 WP_268082350.1 LysR family transcriptional regulator -
P8T11_RS14885 (P8T11_14885) 3349951..3350226 - 276 WP_268081220.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8T11_RS14890 (P8T11_14890) 3350260..3350478 - 219 WP_268081219.1 stability determinant Antitoxin
P8T11_RS14895 (P8T11_14895) 3350804..3351262 + 459 WP_268081218.1 hypothetical protein -
P8T11_RS14900 (P8T11_14900) 3351280..3352227 + 948 WP_268081217.1 sensor domain-containing diguanylate cyclase -
P8T11_RS14905 (P8T11_14905) 3352477..3353715 + 1239 WP_268081216.1 sulfite oxidase -
P8T11_RS14910 (P8T11_14910) 3353816..3354103 + 288 WP_268081215.1 cytochrome c -
P8T11_RS14915 (P8T11_14915) 3354152..3354637 - 486 WP_268081214.1 DUF2214 domain-containing protein -
P8T11_RS14920 (P8T11_14920) 3354656..3355042 - 387 WP_268081213.1 DUF6152 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10350.74 Da        Isoelectric Point: 5.0264

>T276135 WP_268081220.1 NZ_CP121261:c3350226-3349951 [Achromobacter spanius]
MLPIFWSASALDDLDEITNYIAEYDVHAAIGMHELIENAVHPASEHPYLYRPGRVPGTREIVAHPNYILVYEVRADHIGV
IAVMHARQEYP

Download         Length: 276 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8234.24 Da        Isoelectric Point: 9.9898

>AT276135 WP_268081219.1 NZ_CP121261:c3350478-3350260 [Achromobacter spanius]
MSPTLSPIVSEFETEEQAVSYDRWFRAKVQASRDDPRPSIPHDAAMARIREKLAKKLADHDAAPATRRSRDR

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References