Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1596993..1597660 Replicon chromosome
Accession NZ_CP121261
Organism Achromobacter spanius strain LIG8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P8T11_RS06985 Protein ID WP_268077631.1
Coordinates 1597241..1597660 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P8T11_RS06980 Protein ID WP_268077632.1
Coordinates 1596993..1597244 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T11_RS06960 (P8T11_06960) 1592231..1594198 - 1968 WP_268077636.1 NYN domain-containing protein -
P8T11_RS06965 (P8T11_06965) 1594496..1595395 + 900 WP_268077635.1 MotA/TolQ/ExbB proton channel family protein -
P8T11_RS06970 (P8T11_06970) 1595392..1596375 + 984 WP_268077634.1 OmpA family protein -
P8T11_RS06975 (P8T11_06975) 1596539..1596892 + 354 WP_268077633.1 YciI family protein -
P8T11_RS06980 (P8T11_06980) 1596993..1597244 + 252 WP_268077632.1 Arc family DNA-binding protein Antitoxin
P8T11_RS06985 (P8T11_06985) 1597241..1597660 + 420 WP_268077631.1 type II toxin-antitoxin system VapC family toxin Toxin
P8T11_RS06990 (P8T11_06990) 1597802..1598212 + 411 WP_268077630.1 YciI family protein -
P8T11_RS06995 (P8T11_06995) 1598231..1598638 + 408 WP_268077629.1 VOC family protein -
P8T11_RS07000 (P8T11_07000) 1598635..1599909 + 1275 WP_268077628.1 RNA polymerase sigma factor -
P8T11_RS07005 (P8T11_07005) 1599996..1600865 + 870 WP_268077627.1 AraC family transcriptional regulator -
P8T11_RS07010 (P8T11_07010) 1600947..1601906 + 960 WP_268077626.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin

Arc-like DNA binding domain

(10-46)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14660.88 Da        Isoelectric Point: 4.8181

>T276133 WP_268077631.1 NZ_CP121261:1597241-1597660 [Achromobacter spanius]
MILLDTNVISEPLRQAPADAVIEWIDRQPLETLFLSAVTVAELRFGVACMPVGKRRDALHGDLEQRVLALFAGRILAFDT
SASLEYVALMARARASGQAIGGPDGYIAATAAAHGMSVATRDVAPFEAAGVSVINPWGA

Download         Length: 420 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9284.64 Da        Isoelectric Point: 8.9326

>AT276133 WP_268077632.1 NZ_CP121261:1596993-1597244 [Achromobacter spanius]
MPMLTVRNISEEVHRALRVRAAQHGRSTEAEVRAILEDAVKPEGRVKLGSLLLQIGRQARLTDEEAALFDQRDKAPAAPP
RFE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References