Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-DUF971
Location 2066296..2066881 Replicon chromosome
Accession NZ_CP121246
Organism Agrobacterium pusense strain 973_Rhizob3

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag P9K39_RS22550 Protein ID WP_278067940.1
Coordinates 2066579..2066881 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag P9K39_RS22545 Protein ID WP_278067939.1
Coordinates 2066296..2066586 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9K39_RS22525 (P9K39_22525) 2062399..2063406 + 1008 WP_278067935.1 iron-siderophore ABC transporter substrate-binding protein -
P9K39_RS22530 (P9K39_22530) 2063403..2064446 + 1044 WP_278067936.1 iron ABC transporter permease -
P9K39_RS22535 (P9K39_22535) 2064449..2065483 + 1035 WP_278067937.1 iron chelate uptake ABC transporter family permease subunit -
P9K39_RS22540 (P9K39_22540) 2065480..2066292 + 813 WP_278067938.1 ABC transporter ATP-binding protein -
P9K39_RS22545 (P9K39_22545) 2066296..2066586 - 291 WP_278067939.1 putative addiction module antidote protein Antitoxin
P9K39_RS22550 (P9K39_22550) 2066579..2066881 - 303 WP_278067940.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9K39_RS22555 (P9K39_22555) 2067043..2067915 - 873 WP_278067941.1 AraC family transcriptional regulator -
P9K39_RS22560 (P9K39_22560) 2068048..2069262 + 1215 WP_278067942.1 amino acid ABC transporter substrate-binding protein -
P9K39_RS22565 (P9K39_22565) 2069333..2070205 + 873 WP_045533916.1 branched-chain amino acid ABC transporter permease -
P9K39_RS22570 (P9K39_22570) 2070202..2071110 + 909 WP_035208323.1 branched-chain amino acid ABC transporter permease -
P9K39_RS22575 (P9K39_22575) 2071107..2071835 + 729 WP_112637227.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-83)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11124.70 Da        Isoelectric Point: 9.5496

>T276127 WP_278067940.1 NZ_CP121246:c2066881-2066579 [Agrobacterium pusense]
MQIKQSTTFKKWFGKLKDERGKAIIASRLNRLSFGHAGDVAPVGNGISELRIHYGPGYRVYFIISDDVVVVLLCGGNKST
QEKDIRAARVIAAQWSDDDE

Download         Length: 303 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10346.72 Da        Isoelectric Point: 6.2208

>AT276127 WP_278067939.1 NZ_CP121246:c2066586-2066296 [Agrobacterium pusense]
MSEKFTNFNPAEHLKSDEAIEVFLEDAFATNDAAYIANALGVIARAKGMTRVARETGLAREHLYKSLSEAGNPTLETTIA
VLNALGLQLTSKHKAA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References