Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 2050311..2050855 Replicon chromosome
Accession NZ_CP121245
Organism Agrobacterium pusense strain 973_Rhizob3

Toxin (Protein)


Gene name parE Uniprot ID U4PRC3
Locus tag P9K39_RS09815 Protein ID WP_004440407.1
Coordinates 2050565..2050855 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID U4PRA7
Locus tag P9K39_RS09810 Protein ID WP_022555750.1
Coordinates 2050311..2050562 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9K39_RS09785 (P9K39_09785) 2045409..2046098 - 690 WP_003520496.1 HAD family hydrolase -
P9K39_RS09790 (P9K39_09790) 2046313..2046993 + 681 WP_004440402.1 GntR family transcriptional regulator -
P9K39_RS09795 (P9K39_09795) 2047034..2047495 + 462 WP_072494876.1 DUF1284 domain-containing protein -
P9K39_RS09800 (P9K39_09800) 2047455..2048555 - 1101 WP_278067271.1 hypothetical protein -
P9K39_RS09805 (P9K39_09805) 2048792..2049937 + 1146 WP_004440405.1 site-specific DNA-methyltransferase -
P9K39_RS09810 (P9K39_09810) 2050311..2050562 + 252 WP_022555750.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
P9K39_RS09815 (P9K39_09815) 2050565..2050855 + 291 WP_004440407.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P9K39_RS09820 (P9K39_09820) 2050887..2051498 - 612 WP_022555751.1 HAD family phosphatase -
P9K39_RS09825 (P9K39_09825) 2051495..2052598 - 1104 WP_278067272.1 A/G-specific adenine glycosylase -
P9K39_RS09830 (P9K39_09830) 2052696..2053223 + 528 WP_006699987.1 DUF721 domain-containing protein -
P9K39_RS09835 (P9K39_09835) 2053352..2054032 + 681 WP_006309853.1 DsbA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(2-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11253.77 Da        Isoelectric Point: 6.6456

>T276126 WP_004440407.1 NZ_CP121245:2050565-2050855 [Agrobacterium pusense]
MGFRLSLPAEEDVIRIAQEGIDLFGPQQARKYHRELFAIFDLISRNPRIARERNELSPSVRIHPFRAHLVVYRVEADDDV
LIVRVRHGHEDWGNEP

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9316.56 Da        Isoelectric Point: 6.9801

>AT276126 WP_022555750.1 NZ_CP121245:2050311-2050562 [Agrobacterium pusense]
MVTMNISLPGQMKEWVEAQSKTGRYSNASDYVRDLIRKDQERSEKIAAMQGLVDEGLQAPSGHRCEDALFAEAEARSMKR
KIG

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB U4PRC3

Antitoxin

Source ID Structure
AlphaFold DB A0A098RRB9

References