Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4314007..4314241 | Replicon | chromosome |
| Accession | NZ_CP121223 | ||
| Organism | Shigella flexneri 2a strain Sflex 21-42 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4314008..4314111 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4314007..4314241 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P5F89_RS23590 | 4309439..4309906 | - | 468 | Protein_4190 | DNA-binding transcriptional regulator PgrR | - |
| P5F89_RS23595 | 4309970..4310280 | + | 311 | Protein_4191 | transposase | - |
| P5F89_RS23600 | 4310323..4311532 | - | 1210 | Protein_4192 | IS3 family transposase | - |
| P5F89_RS23605 | 4311587..4312435 | + | 849 | Protein_4193 | IS3-like element IS600 family transposase | - |
| P5F89_RS23610 | 4312552..4312833 | + | 282 | WP_005127484.1 | excisionase | - |
| P5F89_RS23615 | 4312799..4313876 | + | 1078 | Protein_4195 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 4314007..4314241 | + | 235 | - | - | Antitoxin |
| - | 4314008..4314111 | - | 104 | - | - | Toxin |
| P5F89_RS23620 | 4314269..4314610 | - | 342 | WP_000976476.1 | YebY family protein | - |
| P5F89_RS23625 | 4314623..4315495 | - | 873 | Protein_4197 | copper homeostasis membrane protein CopD | - |
| P5F89_RS23630 | 4315499..4315873 | - | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| P5F89_RS23635 | 4316012..4316242 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| P5F89_RS23640 | 4316344..4317000 | + | 657 | Protein_4200 | carbon-nitrogen hydrolase family protein YobB | - |
| P5F89_RS23645 | 4317024..4317686 | + | 663 | WP_000944268.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T276101 NZ_CP121223:c4314111-4314008 [Shigella flexneri 2a]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT276101 NZ_CP121223:4314007-4314241 [Shigella flexneri 2a]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
