Detailed information of TA system TA276074

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /HTH_XRE(antitoxin)
• Location: 2136447..2137253
• Replicon: chromosome
• Accession: NZ_CP121204
• Organism: Staphylococcus aureus strain SA0907

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: P7F77_RS10735
• Protein ID: WP_000525003.1
• Coordinates: 2136789..2137253 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: P7F77_RS10730
• Protein ID: WP_001573842.1
• Coordinates: 2136447..2136776 (+)
• Length: 110 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	scn / chp / sak	2097654..2140691	43037

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (10-65)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 18156.52 Da
• Isoelectric Point: 4.7927

>T276074 WP_000525003.1 NZ_CP121204:2136789-2137253 [Staphylococcus aureus]
MGLYEETLIQHDYIEIREADVLPDNLDGVWLGDLILIKRGLSDREKAGILFEELAHNKLTYGDIADYSKFNNRKFENYAR
RHGFISAVPLREIVEAYNYGVRNLYELSEYLQLSEEYILEAIEQYKKIYGIGTHYGEYSITFEPLRVFKLHHID

Nucleotide

• Length: 465 bp

Antitoxin

Protein

• Length: 110 a.a.
• Molecular weight: 12730.33 Da
• Isoelectric Point: 6.4836

>AT276074 WP_001573842.1 NZ_CP121204:2136447-2136776 [Staphylococcus aureus]
MRNNDEIITIIKTSMKEQNLSLSELARRVGVAKSAVSRYLNLTREFPLNRAEDFAKALSISTEYLLGFEKSEQKQEEPQH
RAAHLEGELTDDEWQRVLDYADYIRSKRK

Nucleotide

• Length: 330 bp