276031

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 2151897..2152368 Replicon chromosome
Accession NZ_CP121193
Organism Halomonas sp. CKK8

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag P8934_RS10320 Protein ID WP_278030954.1
Coordinates 2151897..2152163 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag P8934_RS10325 Protein ID WP_278030955.1
Coordinates 2152147..2152368 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8934_RS10295 (P8934_10295) 2148779..2149378 - 600 WP_278030950.1 inorganic diphosphatase -
P8934_RS10300 (P8934_10300) 2149708..2150088 - 381 Protein_2021 phasin family protein -
P8934_RS10305 (P8934_10305) 2150385..2151092 + 708 WP_278030951.1 transposase -
P8934_RS10310 (P8934_10310) 2151230..2151529 + 300 WP_278030952.1 type II toxin-antitoxin system RelE/ParE family toxin -
P8934_RS10315 (P8934_10315) 2151526..2151822 + 297 WP_278030953.1 putative addiction module antidote protein -
P8934_RS10320 (P8934_10320) 2151897..2152163 - 267 WP_278030954.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8934_RS10325 (P8934_10325) 2152147..2152368 - 222 WP_278030955.1 TraY domain-containing protein Antitoxin
P8934_RS10330 (P8934_10330) 2152682..2153050 - 369 WP_278030956.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
P8934_RS10335 (P8934_10335) 2153480..2155276 + 1797 WP_278030957.1 type IV-A pilus assembly ATPase PilB -
P8934_RS10340 (P8934_10340) 2155565..2156797 + 1233 WP_278030958.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Relaxosome protein TraY

(3-48)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10575.29 Da        Isoelectric Point: 10.5507

>T276031 WP_278030954.1 NZ_CP121193:c2152163-2151897 [Halomonas sp. CKK8]
VTWKVEYLASAAKSFKKIDPQHRRRIRAYLEERVVALEHPRQLGKPLRGELTEFRRYRVGDYRIICQIQDDRLVVLVVRA
AHRKDVYE

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8506.67 Da        Isoelectric Point: 5.6158

>AT276031 WP_278030955.1 NZ_CP121193:c2152368-2152147 [Halomonas sp. CKK8]
MPISLRLDPDIEARLAHLARATGRSKTFYLRKLIAEHLDELEDAYLAEHALEQLRQGRDRVMTSEAFWRDLEG

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References