Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 2151230..2151822 Replicon chromosome
Accession NZ_CP121193
Organism Halomonas sp. CKK8

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag P8934_RS10310 Protein ID WP_278030952.1
Coordinates 2151230..2151529 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag P8934_RS10315 Protein ID WP_278030953.1
Coordinates 2151526..2151822 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8934_RS10290 (P8934_10290) 2146829..2148409 - 1581 WP_278030949.1 acetyl-CoA hydrolase/transferase family protein -
P8934_RS10295 (P8934_10295) 2148779..2149378 - 600 WP_278030950.1 inorganic diphosphatase -
P8934_RS10300 (P8934_10300) 2149708..2150088 - 381 Protein_2021 phasin family protein -
P8934_RS10305 (P8934_10305) 2150385..2151092 + 708 WP_278030951.1 transposase -
P8934_RS10310 (P8934_10310) 2151230..2151529 + 300 WP_278030952.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8934_RS10315 (P8934_10315) 2151526..2151822 + 297 WP_278030953.1 putative addiction module antidote protein Antitoxin
P8934_RS10320 (P8934_10320) 2151897..2152163 - 267 WP_278030954.1 type II toxin-antitoxin system RelE/ParE family toxin -
P8934_RS10325 (P8934_10325) 2152147..2152368 - 222 WP_278030955.1 TraY domain-containing protein -
P8934_RS10330 (P8934_10330) 2152682..2153050 - 369 WP_278030956.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
P8934_RS10335 (P8934_10335) 2153480..2155276 + 1797 WP_278030957.1 type IV-A pilus assembly ATPase PilB -
P8934_RS10340 (P8934_10340) 2155565..2156797 + 1233 WP_278030958.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(22-87)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11261.05 Da        Isoelectric Point: 10.6190

>T276030 WP_278030952.1 NZ_CP121193:2151230-2151529 [Halomonas sp. CKK8]
MLDIKQTDTFRKWERKLRDQRAKAMIAARVFRLANGLPGDIKPVGNGISELRIHYGPGYRIYFKKRGNDIIILLCGGNKS
SQQVDIEAAKRLASEWEAS

Download         Length: 300 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10565.02 Da        Isoelectric Point: 4.4929

>AT276030 WP_278030953.1 NZ_CP121193:2151526-2151822 [Halomonas sp. CKK8]
MTEKLYDYDPAAALESEEAIAVFLADALETGDSAYIAKAMGVVARAKGMTELARETGLSREQLYRSFSEQGNPTLKTMLA
VMRALGVDLTARPHEPAA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References