276014

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 932843..933503 Replicon chromosome
Accession NZ_CP121189
Organism Salmonella enterica subsp. enterica serovar Indiana strain S1467

Toxin (Protein)


Gene name cptA Uniprot ID A0A3V4SJP5
Locus tag P6164_RS04570 Protein ID WP_000244755.1
Coordinates 933090..933503 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag P6164_RS04565 Protein ID WP_000351186.1
Coordinates 932843..933109 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6164_RS04545 (929152) 929152..929463 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
P6164_RS04550 (929627) 929627..930286 + 660 WP_000250289.1 hemolysin III family protein -
P6164_RS04555 (930544) 930544..931530 + 987 WP_023226548.1 IS110 family transposase -
P6164_RS04560 (931613) 931613..932593 - 981 WP_017441090.1 tRNA-modifying protein YgfZ -
P6164_RS04565 (932843) 932843..933109 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
P6164_RS04570 (933090) 933090..933503 + 414 WP_000244755.1 protein YgfX Toxin
P6164_RS04575 (933556) 933556..934077 - 522 WP_001055885.1 flavodoxin FldB -
P6164_RS04580 (934190) 934190..935086 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
P6164_RS04585 (935110) 935110..935823 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P6164_RS04590 (935829) 935829..937562 + 1734 WP_023227724.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16164.10 Da        Isoelectric Point: 10.2118

>T276014 WP_000244755.1 NZ_CP121189:933090-933503 [Salmonella enterica subsp. enterica serovar Indiana]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLHPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT276014 WP_000351186.1 NZ_CP121189:932843-933109 [Salmonella enterica subsp. enterica serovar Indiana]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SJP5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References