Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2659782..2660053 Replicon chromosome
Accession NZ_CP121157
Organism Escherichia coli strain E89

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2659820..2659923 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2659782..2660053 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6H86_RS13005 2656939..2658378 + 1440 WP_032187451.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P6H86_RS13010 2658496..2658732 + 237 WP_001338166.1 YebV family protein -
P6H86_RS13015 2658837..2659028 + 192 WP_001338167.1 YebW family protein -
P6H86_RS13020 2659029..2659685 - 657 WP_066018957.1 protein-serine/threonine phosphatase -
- 2659782..2660053 + 272 - - Antitoxin
- 2659820..2659923 - 104 - - Toxin
P6H86_RS13025 2660081..2660422 - 342 WP_000976472.1 YebY family protein -
P6H86_RS13030 2660435..2661307 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
P6H86_RS13035 2661311..2661685 - 375 WP_066018956.1 CopC domain-containing protein YobA -
P6H86_RS13040 2661824..2662054 + 231 WP_000916763.1 DNA polymerase III subunit theta -
P6H86_RS13045 2662156..2662812 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
P6H86_RS13050 2662836..2663498 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T275990 NZ_CP121157:c2659923-2659820 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT275990 NZ_CP121157:2659782-2660053 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References