Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2355189..2355460 Replicon chromosome
Accession NZ_CP121151
Organism Escherichia coli strain E47

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2355319..2355422 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2355189..2355460 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6H31_RS11785 2351744..2352406 - 663 WP_000944256.1 exodeoxyribonuclease X -
P6H31_RS11790 2352430..2353086 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
P6H31_RS11795 2353188..2353418 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P6H31_RS11800 2353557..2353931 + 375 WP_000204699.1 CopC domain-containing protein YobA -
P6H31_RS11805 2353935..2354807 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
P6H31_RS11810 2354820..2355161 + 342 WP_000976472.1 YebY family protein -
- 2355189..2355460 - 272 - - Antitoxin
- 2355319..2355422 + 104 - - Toxin
P6H31_RS11815 2355557..2356213 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
P6H31_RS11820 2356214..2356405 - 192 WP_001296140.1 YebW family protein -
P6H31_RS11825 2356510..2356746 - 237 WP_001295499.1 YebV family protein -
P6H31_RS11830 2356864..2358303 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T275905 NZ_CP121151:2355319-2355422 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT275905 NZ_CP121151:c2355460-2355189 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References