Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2189547..2189818 Replicon chromosome
Accession NZ_CP121149
Organism Escherichia coli strain E14

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2189677..2189780 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2189547..2189818 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P1I99_RS10615 2186102..2186764 - 663 WP_000944256.1 exodeoxyribonuclease X -
P1I99_RS10620 2186788..2187444 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
P1I99_RS10625 2187546..2187776 - 231 WP_000916763.1 DNA polymerase III subunit theta -
P1I99_RS10630 2187915..2188289 + 375 WP_000204699.1 CopC domain-containing protein YobA -
P1I99_RS10635 2188293..2189165 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
P1I99_RS10640 2189178..2189519 + 342 WP_000976492.1 YebY family protein -
- 2189547..2189818 - 272 - - Antitoxin
- 2189677..2189780 + 104 - - Toxin
P1I99_RS10645 2189915..2190571 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
P1I99_RS10650 2190572..2190763 - 192 WP_001296140.1 YebW family protein -
P1I99_RS10655 2190868..2191104 - 237 WP_001295499.1 YebV family protein -
P1I99_RS10660 2191222..2192661 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T275884 NZ_CP121149:2189677-2189780 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT275884 NZ_CP121149:c2189818-2189547 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References