Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2755755..2756026 Replicon chromosome
Accession NZ_CP121147
Organism Escherichia coli strain E20

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2755793..2755895 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2755755..2756026 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6H07_RS13225 2752912..2754351 + 1440 WP_024179479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P6H07_RS13230 2754469..2754705 + 237 WP_001295499.1 YebV family protein -
P6H07_RS13235 2754810..2755001 + 192 WP_001296140.1 YebW family protein -
P6H07_RS13240 2755002..2755658 - 657 WP_000812752.1 protein-serine/threonine phosphatase -
- 2755755..2756026 + 272 - - Antitoxin
- 2755793..2755895 - 103 - - Toxin
P6H07_RS13245 2756054..2756395 - 342 WP_000976484.1 YebY family protein -
P6H07_RS13250 2756408..2757280 - 873 WP_000879323.1 copper homeostasis membrane protein CopD -
P6H07_RS13255 2757284..2757658 - 375 WP_000168737.1 CopC domain-containing protein YobA -
P6H07_RS13260 2757797..2758027 + 231 WP_000916763.1 DNA polymerase III subunit theta -
P6H07_RS13265 2758129..2758785 + 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
P6H07_RS13270 2758809..2759471 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275860 NZ_CP121147:c2755895-2755793 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT275860 NZ_CP121147:2755755-2756026 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References