275843

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3352375..3352520 Replicon chromosome
Accession NZ_CP121145
Organism Klebsiella pneumoniae strain UHD-56_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3352382..3352484 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3352375..3352520 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T43_RS16080 (P8T43_16075) 3347907..3349340 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P8T43_RS16085 (P8T43_16080) 3349456..3349695 + 240 WP_002911393.1 YebV family protein -
P8T43_RS16090 (P8T43_16085) 3349793..3349984 + 192 WP_002911395.1 YebW family protein -
P8T43_RS16095 (P8T43_16090) 3349981..3350634 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T43_RS16100 (P8T43_16095) 3350791..3351759 + 969 WP_004151446.1 VirK/YbjX family protein -
P8T43_RS16105 (P8T43_16100) 3351864..3352007 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3352375..3352520 + 146 - - Antitoxin
- 3352382..3352484 - 103 - - Toxin
P8T43_RS16110 (P8T43_16105) 3352643..3352981 - 339 WP_002911404.1 YebY family protein -
P8T43_RS16115 (P8T43_16110) 3352998..3353867 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T43_RS16120 (P8T43_16115) 3353871..3354245 - 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T43_RS16125 (P8T43_16120) 3354358..3354588 + 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T43_RS16130 (P8T43_16125) 3354667..3355326 + 660 WP_002911407.1 exodeoxyribonuclease X -
P8T43_RS16135 (P8T43_16130) 3355330..3357390 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275843 NZ_CP121145:c3352484-3352382 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275843 NZ_CP121145:3352375-3352520 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References