Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4567341..4567486 Replicon chromosome
Accession NZ_CP121141
Organism Klebsiella pneumoniae strain UHD-58_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4567348..4567450 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4567341..4567486 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T47_RS22095 (P8T47_22095) 4562873..4564306 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P8T47_RS22100 (P8T47_22100) 4564422..4564661 + 240 WP_002911393.1 YebV family protein -
P8T47_RS22105 (P8T47_22105) 4564759..4564950 + 192 WP_002911395.1 YebW family protein -
P8T47_RS22110 (P8T47_22110) 4564947..4565600 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T47_RS22115 (P8T47_22115) 4565757..4566725 + 969 WP_004151446.1 VirK/YbjX family protein -
P8T47_RS22120 (P8T47_22120) 4566830..4566973 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4567341..4567486 + 146 - - Antitoxin
- 4567348..4567450 - 103 - - Toxin
P8T47_RS22125 (P8T47_22125) 4567609..4567947 - 339 WP_002911404.1 YebY family protein -
P8T47_RS22130 (P8T47_22130) 4567964..4568833 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T47_RS22135 (P8T47_22135) 4568837..4569211 - 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T47_RS22140 (P8T47_22140) 4569324..4569554 + 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T47_RS22145 (P8T47_22145) 4569633..4570292 + 660 WP_002911407.1 exodeoxyribonuclease X -
P8T47_RS22150 (P8T47_22150) 4570296..4572356 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275817 NZ_CP121141:c4567450-4567348 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275817 NZ_CP121141:4567341-4567486 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References