Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3056542..3056687 Replicon chromosome
Accession NZ_CP121139
Organism Klebsiella pneumoniae strain UHD-4_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3056549..3056651 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3056542..3056687 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T35_RS14670 (P8T35_14670) 3052074..3053507 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P8T35_RS14675 (P8T35_14675) 3053623..3053862 + 240 WP_002911393.1 YebV family protein -
P8T35_RS14680 (P8T35_14680) 3053960..3054151 + 192 WP_002911395.1 YebW family protein -
P8T35_RS14685 (P8T35_14685) 3054148..3054801 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T35_RS14690 (P8T35_14690) 3054958..3055926 + 969 WP_004151446.1 VirK/YbjX family protein -
P8T35_RS14695 (P8T35_14695) 3056031..3056174 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3056542..3056687 + 146 - - Antitoxin
- 3056549..3056651 - 103 - - Toxin
P8T35_RS14700 (P8T35_14700) 3056810..3057148 - 339 WP_002911404.1 YebY family protein -
P8T35_RS14705 (P8T35_14705) 3057165..3058034 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T35_RS14710 (P8T35_14710) 3058038..3058412 - 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T35_RS14715 (P8T35_14715) 3058525..3058755 + 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T35_RS14720 (P8T35_14720) 3058834..3059493 + 660 WP_002911407.1 exodeoxyribonuclease X -
P8T35_RS14725 (P8T35_14725) 3059497..3061557 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275797 NZ_CP121139:c3056651-3056549 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275797 NZ_CP121139:3056542-3056687 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References