Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 754472..754617 Replicon chromosome
Accession NZ_CP121137
Organism Klebsiella pneumoniae strain UHD-33_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 754508..754610 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 754472..754617 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T49_RS03635 (P8T49_03635) 749602..751662 + 2061 WP_004148850.1 oligopeptidase B -
P8T49_RS03640 (P8T49_03640) 751666..752325 - 660 WP_002911407.1 exodeoxyribonuclease X -
P8T49_RS03645 (P8T49_03645) 752404..752634 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T49_RS03650 (P8T49_03650) 752747..753121 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T49_RS03655 (P8T49_03655) 753125..753994 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T49_RS03660 (P8T49_03660) 754011..754349 + 339 WP_002911404.1 YebY family protein -
- 754472..754617 - 146 - - Antitoxin
- 754508..754610 + 103 - - Toxin
P8T49_RS03665 (P8T49_03665) 754985..755128 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P8T49_RS03670 (P8T49_03670) 755233..756201 - 969 WP_004151446.1 VirK/YbjX family protein -
P8T49_RS03675 (P8T49_03675) 756358..757011 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T49_RS03680 (P8T49_03680) 757008..757199 - 192 WP_002911395.1 YebW family protein -
P8T49_RS03685 (P8T49_03685) 757297..757536 - 240 WP_002911393.1 YebV family protein -
P8T49_RS03690 (P8T49_03690) 757652..759085 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275777 NZ_CP121137:754508-754610 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275777 NZ_CP121137:c754617-754472 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References