Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4567363..4567508 | Replicon | chromosome |
| Accession | NZ_CP121135 | ||
| Organism | Klebsiella pneumoniae strain UHD-41_PH | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4567370..4567472 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4567363..4567508 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| P8T41_RS22100 (P8T41_22095) | 4562895..4564328 | + | 1434 | WP_032415191.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| P8T41_RS22105 (P8T41_22100) | 4564444..4564683 | + | 240 | WP_002911393.1 | YebV family protein | - |
| P8T41_RS22110 (P8T41_22105) | 4564781..4564972 | + | 192 | WP_002911395.1 | YebW family protein | - |
| P8T41_RS22115 (P8T41_22110) | 4564969..4565622 | - | 654 | WP_032415192.1 | protein-serine/threonine phosphatase | - |
| P8T41_RS22120 (P8T41_22115) | 4565779..4566747 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| P8T41_RS22125 (P8T41_22120) | 4566852..4566995 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 4567363..4567508 | + | 146 | - | - | Antitoxin |
| - | 4567370..4567472 | - | 103 | - | - | Toxin |
| P8T41_RS22130 (P8T41_22125) | 4567631..4567969 | - | 339 | WP_002911404.1 | YebY family protein | - |
| P8T41_RS22135 (P8T41_22130) | 4567986..4568855 | - | 870 | WP_004175431.1 | copper homeostasis membrane protein CopD | - |
| P8T41_RS22140 (P8T41_22135) | 4568859..4569233 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| P8T41_RS22145 (P8T41_22140) | 4569346..4569576 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| P8T41_RS22150 (P8T41_22145) | 4569655..4570314 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| P8T41_RS22155 (P8T41_22150) | 4570318..4572378 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T275772 NZ_CP121135:c4567472-4567370 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT275772 NZ_CP121135:4567363-4567508 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
