Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3298063..3298208 Replicon chromosome
Accession NZ_CP121133
Organism Klebsiella pneumoniae strain UHD-45_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3298070..3298172 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3298063..3298208 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T31_RS15820 (P8T31_15820) 3293595..3295028 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P8T31_RS15825 (P8T31_15825) 3295144..3295383 + 240 WP_002911393.1 YebV family protein -
P8T31_RS15830 (P8T31_15830) 3295481..3295672 + 192 WP_002911395.1 YebW family protein -
P8T31_RS15835 (P8T31_15835) 3295669..3296322 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T31_RS15840 (P8T31_15840) 3296479..3297447 + 969 WP_004151446.1 VirK/YbjX family protein -
P8T31_RS15845 (P8T31_15845) 3297552..3297695 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3298063..3298208 + 146 - - Antitoxin
- 3298070..3298172 - 103 - - Toxin
P8T31_RS15850 (P8T31_15850) 3298331..3298669 - 339 WP_002911404.1 YebY family protein -
P8T31_RS15855 (P8T31_15855) 3298686..3299555 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T31_RS15860 (P8T31_15860) 3299559..3299933 - 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T31_RS15865 (P8T31_15865) 3300046..3300276 + 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T31_RS15870 (P8T31_15870) 3300355..3301014 + 660 WP_002911407.1 exodeoxyribonuclease X -
P8T31_RS15875 (P8T31_15875) 3301018..3303078 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275753 NZ_CP121133:c3298172-3298070 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275753 NZ_CP121133:3298063-3298208 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References