Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3193688..3193833 Replicon chromosome
Accession NZ_CP121129
Organism Klebsiella pneumoniae strain UHD-49_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3193695..3193797 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3193688..3193833 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T37_RS15340 (P8T37_15340) 3189220..3190653 + 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
P8T37_RS15345 (P8T37_15345) 3190769..3191008 + 240 WP_002911393.1 YebV family protein -
P8T37_RS15350 (P8T37_15350) 3191106..3191297 + 192 WP_002911395.1 YebW family protein -
P8T37_RS15355 (P8T37_15355) 3191294..3191947 - 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T37_RS15360 (P8T37_15360) 3192104..3193072 + 969 WP_004151446.1 VirK/YbjX family protein -
P8T37_RS15365 (P8T37_15365) 3193177..3193320 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3193688..3193833 + 146 - - Antitoxin
- 3193695..3193797 - 103 - - Toxin
P8T37_RS15370 (P8T37_15370) 3193956..3194294 - 339 WP_002911404.1 YebY family protein -
P8T37_RS15375 (P8T37_15375) 3194311..3195180 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T37_RS15380 (P8T37_15380) 3195184..3195558 - 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T37_RS15385 (P8T37_15385) 3195671..3195901 + 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T37_RS15390 (P8T37_15390) 3195980..3196639 + 660 WP_002911407.1 exodeoxyribonuclease X -
P8T37_RS15395 (P8T37_15395) 3196643..3198703 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275722 NZ_CP121129:c3193797-3193695 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275722 NZ_CP121129:3193688-3193833 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References