Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1596750..1596895 Replicon chromosome
Accession NZ_CP121127
Organism Klebsiella pneumoniae strain UHD-53_PH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1596786..1596888 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1596750..1596895 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8T39_RS07950 (P8T39_07950) 1591880..1593940 + 2061 WP_004148850.1 oligopeptidase B -
P8T39_RS07955 (P8T39_07955) 1593944..1594603 - 660 WP_002911407.1 exodeoxyribonuclease X -
P8T39_RS07960 (P8T39_07960) 1594682..1594912 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P8T39_RS07965 (P8T39_07965) 1595025..1595399 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P8T39_RS07970 (P8T39_07970) 1595403..1596272 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
P8T39_RS07975 (P8T39_07975) 1596289..1596627 + 339 WP_002911404.1 YebY family protein -
- 1596750..1596895 - 146 - - Antitoxin
- 1596786..1596888 + 103 - - Toxin
P8T39_RS07980 (P8T39_07980) 1597263..1597406 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P8T39_RS07985 (P8T39_07985) 1597511..1598479 - 969 WP_004151446.1 VirK/YbjX family protein -
P8T39_RS07990 (P8T39_07990) 1598636..1599289 + 654 WP_032415192.1 protein-serine/threonine phosphatase -
P8T39_RS07995 (P8T39_07995) 1599286..1599477 - 192 WP_002911395.1 YebW family protein -
P8T39_RS08000 (P8T39_08000) 1599575..1599814 - 240 WP_002911393.1 YebV family protein -
P8T39_RS08005 (P8T39_08005) 1599930..1601363 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T275703 NZ_CP121127:1596786-1596888 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT275703 NZ_CP121127:c1596895-1596750 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References