Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3508705..3509230 Replicon chromosome
Accession NZ_CP121119
Organism Halomonas sp. M1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P8S54_RS16100 Protein ID WP_281442551.1
Coordinates 3508946..3509230 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P8S54_RS16095 Protein ID WP_281442550.1
Coordinates 3508705..3508956 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8S54_RS16075 (P8S55_16030) 3504854..3505456 + 603 WP_281442547.1 glutathione S-transferase N-terminal domain-containing protein -
P8S54_RS16080 (P8S55_16035) 3505484..3506377 - 894 WP_281442548.1 LysR family transcriptional regulator -
P8S54_RS16085 (P8S55_16040) 3506500..3507717 + 1218 WP_281442549.1 tryptophan synthase subunit beta -
P8S54_RS16090 (P8S55_16045) 3507774..3508592 + 819 WP_281444121.1 tryptophan synthase subunit alpha -
P8S54_RS16095 (P8S55_16050) 3508705..3508956 + 252 WP_281442550.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P8S54_RS16100 (P8S55_16055) 3508946..3509230 + 285 WP_281442551.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8S54_RS16105 (P8S55_16060) 3509273..3509593 + 321 WP_281442552.1 hypothetical protein -
P8S54_RS16110 3509615..3510510 + 896 Protein_3144 dihydrodipicolinate synthase family protein -
P8S54_RS16115 (P8S55_16075) 3510516..3511484 - 969 WP_281442553.1 putative zinc-binding metallopeptidase -
P8S54_RS16120 (P8S55_16080) 3511658..3512224 + 567 WP_281442554.1 pyridoxamine 5'-phosphate oxidase family protein -
P8S54_RS16125 (P8S55_16085) 3512323..3512658 + 336 WP_009100498.1 zinc ribbon domain-containing protein YjdM -
P8S54_RS16130 (P8S55_16090) 3513207..3513638 + 432 WP_281442555.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-75)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11012.07 Da        Isoelectric Point: 10.4268

>T275701 WP_281442551.1 NZ_CP121119:3508946-3509230 [Halomonas sp. M1]
MTYKLRFLPAALKEWEKLSPPVKQQFKKKLAERLETPRVPADKLSGFDACYKIKLRSVGYRLVYEVVDDELFIYVIAVGK
RDKGNVYASLKRRM

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9101.48 Da        Isoelectric Point: 4.7318

>AT275701 WP_281442550.1 NZ_CP121119:3508705-3508956 [Halomonas sp. M1]
MHQVLANFSVSISELKKNPSALLTQASGAPIAVLNHNKPAAYLVPVETYEAMMEMLEDYELAKLVEGRRADKDKAVTVSL
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References