Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 738047..738642 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag P6287_RS22980 Protein ID WP_277975140.1
Coordinates 738047..738424 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag P6287_RS22985 Protein ID WP_110867236.1
Coordinates 738421..738642 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS22960 (P6287_22960) 734647..735960 + 1314 WP_277975139.1 cytochrome c -
P6287_RS22965 (P6287_22965) 736071..736535 - 465 WP_210080080.1 heme-degrading domain-containing protein -
P6287_RS22970 (P6287_22970) 736618..736968 - 351 WP_192414734.1 cupin domain-containing protein -
P6287_RS22975 (P6287_22975) 737114..738037 + 924 WP_192414732.1 glutaminase B -
P6287_RS22980 (P6287_22980) 738047..738424 - 378 WP_277975140.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
P6287_RS22985 (P6287_22985) 738421..738642 - 222 WP_110867236.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
P6287_RS22990 (P6287_22990) 738889..739305 + 417 WP_137387179.1 DUF2946 domain-containing protein -
P6287_RS22995 (P6287_22995) 739378..741114 + 1737 WP_277975141.1 DUF2534 family protein -
P6287_RS23000 (P6287_23000) 741195..742211 - 1017 WP_008108001.1 NAD(P)-dependent alcohol dehydrogenase -
P6287_RS23005 (P6287_23005) 742334..742603 - 270 WP_101761136.1 hypothetical protein -
P6287_RS23010 (P6287_23010) 742884..743444 + 561 WP_217547695.1 thioredoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(2-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-53)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 13942.06 Da        Isoelectric Point: 6.9892

>T275699 WP_277975140.1 NZ_CP121109:c738424-738047 [Pantoea sp. X85]
MIHVSAEEVIALHDYLLKRYAGVAGMPDPGRAEAIVARVINREYYEGIQDIFELAATYWVAISRGHIFADANKRTSLNVT
MLFLKRNGIRVHDRPELVELTVMAATGEAGVPFLANQLRAFFGSH

Download         Length: 378 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8005.92 Da        Isoelectric Point: 4.5203

>AT275699 WP_110867236.1 NZ_CP121109:c738642-738421 [Pantoea sp. X85]
MNKFTYTSARENLSQVLDQAIAGEAVEITRRSGDSAVVISKASFEAYRKAVLDAEFAELMGEFDASNKALTDR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References