Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 725226..725776 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag P6287_RS22915 Protein ID WP_137387189.1
Coordinates 725468..725776 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag P6287_RS22910 Protein ID WP_137387190.1
Coordinates 725226..725465 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS22890 (P6287_22890) 720999..722165 + 1167 WP_277975133.1 lycopene beta-cyclase CrtY -
P6287_RS22895 (P6287_22895) 722162..723643 + 1482 WP_277975134.1 phytoene desaturase -
P6287_RS22900 (P6287_22900) 723640..724569 + 930 WP_217547671.1 phytoene/squalene synthase family protein -
P6287_RS22905 (P6287_22905) 724508..725041 - 534 WP_101761117.1 sterol desaturase family protein -
P6287_RS22910 (P6287_22910) 725226..725465 + 240 WP_137387190.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
P6287_RS22915 (P6287_22915) 725468..725776 + 309 WP_137387189.1 CcdB family protein Toxin
P6287_RS22920 (P6287_22920) 725908..727098 + 1191 WP_277975135.1 MFS transporter -
P6287_RS22925 (P6287_22925) 727091..727435 - 345 WP_192413440.1 helix-turn-helix transcriptional regulator -
P6287_RS22930 (P6287_22930) 727532..728473 - 942 WP_192413442.1 sugar phosphate isomerase/epimerase -
P6287_RS22935 (P6287_22935) 728482..729660 - 1179 WP_277975136.1 Gfo/Idh/MocA family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 12035.88 Da        Isoelectric Point: 5.8576

>T275698 WP_137387189.1 NZ_CP121109:725468-725776 [Pantoea sp. X85]
MQYFIYRNTNRNSEYPYLVDVQSEIIGELASRIVIPLYPLNQFKKKQVERLNPVIKVEGEEFLVMTHEMASVRVSLLGDQ
VMDARVYRQRIKDSVDFVFDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9055.19 Da        Isoelectric Point: 5.7219

>AT275698 WP_137387190.1 NZ_CP121109:725226-725465 [Pantoea sp. X85]
MPSTAVRQKKTVSVTLEPALLEQAREAGLNLSAILSKALHYEIRTTEAERWKRENSEGLQELNRITEEHGLLSDEYRTF

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References