275697

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 717509..718545 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag P6287_RS22870 Protein ID WP_277975130.1
Coordinates 717509..718084 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag P6287_RS22875 Protein ID WP_277975131.1
Coordinates 718084..718545 (-) Length 154 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS22850 (P6287_22850) 712726..713217 - 492 WP_277975126.1 GNAT family N-acetyltransferase -
P6287_RS22855 (P6287_22855) 713657..715084 + 1428 WP_277975127.1 trehalose-6-phosphate synthase -
P6287_RS22860 (P6287_22860) 715126..716307 - 1182 WP_277975128.1 FAD-binding oxidoreductase -
P6287_RS22865 (P6287_22865) 716426..717367 - 942 WP_277975129.1 2-hydroxyacid dehydrogenase -
P6287_RS22870 (P6287_22870) 717509..718084 - 576 WP_277975130.1 PIN domain-containing protein Toxin
P6287_RS22875 (P6287_22875) 718084..718545 - 462 WP_277975131.1 helix-turn-helix domain-containing protein Antitoxin
P6287_RS22880 (P6287_22880) 718802..719707 + 906 WP_101761112.1 polyprenyl synthetase family protein -
P6287_RS22885 (P6287_22885) 719722..720999 + 1278 WP_277975132.1 glycosyltransferase -
P6287_RS22890 (P6287_22890) 720999..722165 + 1167 WP_277975133.1 lycopene beta-cyclase CrtY -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(84-129)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21530.13 Da        Isoelectric Point: 5.6952

>T275697 WP_277975130.1 NZ_CP121109:c718084-717509 [Pantoea sp. X85]
MNHSPYAVVLDACVLYPSILRDVLLRLGLTGLYQPKWTATIQDEWKRNLRTNRPDIAEDQLARTQTLMNKALPDVMVSGF
EPLISGITLPDSNDCHVVAAAIRCKAEVIVTMNLKDFPRNLMAEFEIEALHPDEFIMDLFDLNQALVLKAVNAQRASFRQ
PAMGVTVYLDSLLRQGLPMTVSALDKFRFLI

Download         Length: 576 bp

Antitoxin


Download         Length: 154 a.a.        Molecular weight: 17054.41 Da        Isoelectric Point: 6.6084

>AT275697 WP_277975131.1 NZ_CP121109:c718545-718084 [Pantoea sp. X85]
MKHSILDSLSLPAPKEIEAASRGQRELATYLSTKQETQKISIQDAHNETHQIELPTSALTLLMAVLGELAVGNAVQVVPV
HAELTTQEAANILNVSRPHLVKLLEQGQLPYHKTGRHRRVLFADLMQFKDKRAQESNDAMQELANQGQDLNLY

Download         Length: 462 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References