Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 534293..534995 Replicon plasmid unnamed
Accession NZ_CP121109
Organism Pantoea sp. X85

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag P6287_RS22050 Protein ID WP_192413132.1
Coordinates 534612..534995 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag P6287_RS22045 Protein ID WP_137387307.1
Coordinates 534293..534619 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS22025 (P6287_22025) 530007..530894 + 888 WP_277975035.1 aromatic amino acid DMT transporter YddG -
P6287_RS22030 (P6287_22030) 531053..532255 - 1203 WP_277975036.1 FAD-dependent oxidoreductase -
P6287_RS22035 (P6287_22035) 532310..533245 - 936 WP_277975037.1 AraC family transcriptional regulator -
P6287_RS22040 (P6287_22040) 533357..534190 + 834 WP_277975038.1 oxidoreductase -
P6287_RS22045 (P6287_22045) 534293..534619 - 327 WP_137387307.1 helix-turn-helix domain-containing protein Antitoxin
P6287_RS22050 (P6287_22050) 534612..534995 - 384 WP_192413132.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P6287_RS22055 (P6287_22055) 535270..535521 + 252 WP_110866812.1 regulatory protein YcgZ -
P6287_RS22060 (P6287_22060) 535639..535929 + 291 WP_101761585.1 hypothetical protein -
P6287_RS22065 (P6287_22065) 536137..536487 - 351 WP_277975039.1 DUF3147 family protein -
P6287_RS22070 (P6287_22070) 536514..537377 - 864 WP_277975040.1 substrate-binding domain-containing protein -
P6287_RS22075 (P6287_22075) 537500..538141 - 642 WP_277975041.1 LysE family translocator -
P6287_RS22080 (P6287_22080) 538367..538720 - 354 WP_192234707.1 DUF1428 domain-containing protein -
P6287_RS22085 (P6287_22085) 538815..539585 + 771 WP_277975042.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - hcp/tssD 1..771939 771939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-123)

Antitoxin

Cro/C1-type helix-turn-helix domain

(54-95)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13849.13 Da        Isoelectric Point: 10.2013

>T275695 WP_192413132.1 NZ_CP121109:c534995-534612 [Pantoea sp. X85]
MAIYVLKPFDRNTKGDAINSAKLCKAALEVMAGIYEASFGRGVYKKRIPLVAGKSGGARAVVAFKTEKHLFFVNGYAKSA
FKSSGREISESDLALYKEVAKQLFEMTSEQAKVAINTGKMREVKCDG

Download         Length: 384 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12427.46 Da        Isoelectric Point: 8.5614

>AT275695 WP_137387307.1 NZ_CP121109:c534619-534293 [Pantoea sp. X85]
MVNHLKDLQEIARDFNEIGVVTDELKEKIDSRVRLRELRASLPVLHMMSGDEINQLRQRYNLSQAMLAAYVGMSVGTVVK
WEREEKKPNGAALRLLNLIERKGLEVLQ

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References