Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 2698156..2698787 Replicon chromosome
Accession NZ_CP121108
Organism Pantoea sp. X85

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag P6287_RS12500 Protein ID WP_217548660.1
Coordinates 2698389..2698787 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag P6287_RS12495 Protein ID WP_101763423.1
Coordinates 2698156..2698389 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS12490 (P6287_12490) 2695013..2698084 + 3072 WP_277973805.1 multidrug efflux RND transporter permease subunit MdtC -
P6287_RS12495 (P6287_12495) 2698156..2698389 + 234 WP_101763423.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
P6287_RS12500 (P6287_12500) 2698389..2698787 + 399 WP_217548660.1 tRNA(fMet)-specific endonuclease VapC Toxin
P6287_RS12505 (P6287_12505) 2698804..2700210 + 1407 WP_192411522.1 multidrug transporter subunit MdtD -
P6287_RS12510 (P6287_12510) 2700207..2701592 + 1386 WP_101763347.1 two-component system sensor histidine kinase BaeS -
P6287_RS12515 (P6287_12515) 2701602..2702309 + 708 WP_101763346.1 two-component system response regulator BaeR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15048.31 Da        Isoelectric Point: 8.1127

>T275692 WP_217548660.1 NZ_CP121108:2698389-2698787 [Pantoea sp. X85]
MHRYMLDTHIVIYVIKRRPIEVLERFNANVGRMVISTITLAELFHGSEKSAFPERNLRTVEDFVSRLDVLNYDAKAAFHY
GAIRAELEKNGTPIGLNDLHIAAHARSAALTLVSNNLREFSRVNGLICENWI

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8780.67 Da        Isoelectric Point: 4.2683

>AT275692 WP_101763423.1 NZ_CP121108:2698156-2698389 [Pantoea sp. X85]
MSQGTVFTSNRTQNVRIPADVRFPDDVKNVTVRAIGKERILTPIENAWDSFFLDGPTVSDDFMDERASQEQSEREAF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References