Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2603147..2603737 Replicon chromosome
Accession NZ_CP121108
Organism Pantoea sp. X85

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag P6287_RS12105 Protein ID WP_277973770.1
Coordinates 2603147..2603479 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag P6287_RS12110 Protein ID WP_075808466.1
Coordinates 2603480..2603737 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6287_RS12085 (P6287_12085) 2598308..2599339 - 1032 WP_101763421.1 ABC transporter permease -
P6287_RS12090 (P6287_12090) 2599354..2600838 - 1485 WP_101763420.1 sugar ABC transporter ATP-binding protein -
P6287_RS12095 (P6287_12095) 2600872..2601795 - 924 WP_110866691.1 sugar ABC transporter substrate-binding protein -
P6287_RS12105 (P6287_12105) 2603147..2603479 - 333 WP_277973770.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
P6287_RS12110 (P6287_12110) 2603480..2603737 - 258 WP_075808466.1 antitoxin Antitoxin
P6287_RS12115 (P6287_12115) 2604155..2605459 - 1305 WP_277973771.1 NtaA/DmoA family FMN-dependent monooxygenase -
P6287_RS12120 (P6287_12120) 2605471..2606670 - 1200 WP_277973772.1 M20 family metallopeptidase -
P6287_RS12125 (P6287_12125) 2606768..2607424 - 657 WP_192233454.1 methionine ABC transporter permease -
P6287_RS12130 (P6287_12130) 2607405..2608535 - 1131 WP_277973773.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11782.57 Da        Isoelectric Point: 9.3417

>T275691 WP_277973770.1 NZ_CP121108:c2603479-2603147 [Pantoea sp. X85]
MDRGEIWLVSLDPIAGHEQSGKRPVLIVSKASFNTLTRLPVVVPVTSGGNFAREAGFTVSLDGAGTKTTGVIRCDQPRTI
DMGARNGKRLERIPDAVVNEVLARLEAILS

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9414.97 Da        Isoelectric Point: 4.4620

>AT275691 WP_075808466.1 NZ_CP121108:c2603737-2603480 [Pantoea sp. X85]
MYTTRLKKVGGSIMLAVPPAVLKTLELSMGSEVGMTIDNGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References