275671

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 2579571..2580166 Replicon chromosome
Accession NZ_CP121087
Organism Escherichia coli strain ST3

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag P5670_RS12745 Protein ID WP_024190283.1
Coordinates 2579571..2579921 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID L4JJX7
Locus tag P5670_RS12750 Protein ID WP_001223213.1
Coordinates 2579915..2580166 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P5670_RS12725 (2574945) 2574945..2575967 - 1023 WP_001298067.1 ABC transporter permease -
P5670_RS12730 (2575981) 2575981..2577483 - 1503 WP_001605422.1 sugar ABC transporter ATP-binding protein -
P5670_RS12735 (2577696) 2577696..2578652 - 957 WP_000265933.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
P5670_RS12740 (2578962) 2578962..2579492 + 531 WP_000055075.1 inorganic diphosphatase -
P5670_RS12745 (2579571) 2579571..2579921 - 351 WP_024190283.1 endoribonuclease toxin ChpB Toxin
P5670_RS12750 (2579915) 2579915..2580166 - 252 WP_001223213.1 type II toxin-antitoxin system antitoxin ChpS Antitoxin
P5670_RS12755 (2580378) 2580378..2580719 - 342 WP_001219160.1 gamma-glutamylcyclotransferase -
P5670_RS12760 (2580722) 2580722..2584501 - 3780 WP_000060904.1 autotransporter assembly complex protein TamB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12423.38 Da        Isoelectric Point: 6.2206

>T275671 WP_024190283.1 NZ_CP121087:c2579921-2579571 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMALVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAAGEVVEEALLRLQAVVE

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9331.64 Da        Isoelectric Point: 4.6509

>AT275671 WP_001223213.1 NZ_CP121087:c2580166-2579915 [Escherichia coli]
MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILTPISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGD
EIW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB L4JJX7

References