Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2643255..2643398 Replicon chromosome
Accession NZ_CP121073
Organism Salmonella enterica subsp. enterica serovar Infantis strain R22.2169

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2643257..2643360 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2643255..2643398 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8I07_RS12895 2638385..2638585 + 201 Protein_2527 PagK family vesicle-borne virulence factor -
P8I07_RS12900 2638682..2639193 - 512 Protein_2528 tail fiber assembly protein -
P8I07_RS12905 2639206..2639493 - 288 Protein_2529 macro domain-containing protein -
P8I07_RS12910 2639503..2639718 - 216 Protein_2530 shikimate transporter -
P8I07_RS12915 2639720..2639980 - 261 Protein_2531 DUF1441 family protein -
P8I07_RS12920 2640288..2640455 + 168 WP_000789529.1 lytic enzyme -
P8I07_RS12925 2640712..2641245 - 534 WP_001050883.1 DUF2514 domain-containing protein -
P8I07_RS12930 2641299..2641490 - 192 Protein_2534 glycoside hydrolase family 19 protein -
P8I07_RS12935 2641479..2641940 + 462 Protein_2535 DNA breaking-rejoining protein -
P8I07_RS12940 2642204..2643097 + 894 Protein_2536 tyrosine-type recombinase/integrase -
- 2643255..2643398 + 144 - - Antitoxin
- 2643257..2643360 - 104 - - Toxin
P8I07_RS12945 2643500..2643853 - 354 WP_000722368.1 YebY family protein -
P8I07_RS12950 2643870..2644745 - 876 WP_000979694.1 copper homeostasis membrane protein CopD -
P8I07_RS12955 2644746..2645120 - 375 WP_000168393.1 CopC domain-containing protein YobA -
P8I07_RS12960 2645258..2645488 + 231 WP_000856224.1 DNA polymerase III subunit theta -
P8I07_RS12965 2645596..2646252 + 657 WP_000100256.1 nitrilase-related carbon-nitrogen hydrolase -
P8I07_RS12970 2646276..2646974 + 699 WP_000944278.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sopE2 2623675..2649060 25385


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T275603 NZ_CP121073:c2643360-2643257 [Salmonella enterica subsp. enterica serovar Infantis]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 144 bp

>AT275603 NZ_CP121073:2643255-2643398 [Salmonella enterica subsp. enterica serovar Infantis]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References