Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2469987..2470644 Replicon chromosome
Accession NZ_CP120978
Organism Moellerella wisconsensis strain XJ22MSE3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P8A17_RS10990 Protein ID WP_047255277.1
Coordinates 2469987..2470397 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P8A17_RS10995 Protein ID WP_047255278.1
Coordinates 2470378..2470644 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A17_RS10970 2465252..2466922 - 1671 WP_277850667.1 single-stranded-DNA-specific exonuclease RecJ -
P8A17_RS10975 2466994..2467686 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P8A17_RS10980 2467711..2468622 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
P8A17_RS10985 2468843..2469361 + 519 WP_047255276.1 flavodoxin FldB -
P8A17_RS10990 2469987..2470397 - 411 WP_047255277.1 protein YgfX Toxin
P8A17_RS10995 2470378..2470644 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
P8A17_RS11000 2470905..2471897 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
P8A17_RS11005 2471915..2472535 + 621 WP_241500862.1 HD domain-containing protein -
P8A17_RS11010 2472707..2475586 - 2880 WP_047255281.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T275505 WP_047255277.1 NZ_CP120978:c2470397-2469987 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT275505 WP_047255278.1 NZ_CP120978:c2470644-2470378 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References