Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3133124..3133598 Replicon chromosome
Accession NZ_CP120974
Organism Moellerella wisconsensis strain XJ22MSE2

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag P8A16_RS13750 Protein ID WP_047257106.1
Coordinates 3133124..3133390 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag P8A16_RS13755 Protein ID WP_047257105.1
Coordinates 3133374..3133598 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A16_RS13730 3128444..3129358 - 915 WP_277850218.1 ribonuclease Z -
P8A16_RS13735 3129388..3130989 - 1602 WP_277850219.1 RNA repair transcriptional activator RtcR -
P8A16_RS13740 3131273..3131488 + 216 WP_047257108.1 hypothetical protein -
P8A16_RS13745 3131510..3132637 + 1128 WP_047257107.1 slipin family protein -
P8A16_RS13750 3133124..3133390 - 267 WP_047257106.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P8A16_RS13755 3133374..3133598 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
P8A16_RS13760 3133788..3133916 + 129 WP_269430907.1 hypothetical protein -
P8A16_RS13770 3135403..3136179 - 777 WP_277850221.1 hypothetical protein -
P8A16_RS13775 3136382..3136600 - 219 WP_277850222.1 hypothetical protein -
P8A16_RS13780 3136838..3137614 - 777 WP_277850223.1 hypothetical protein -
P8A16_RS13785 3137595..3137768 - 174 WP_277850224.1 hypothetical protein -
P8A16_RS13790 3137817..3137999 - 183 WP_277850225.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3133995..3134798 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10416.09 Da        Isoelectric Point: 9.5211

>T275501 WP_047257106.1 NZ_CP120974:c3133390-3133124 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATI
GHRREIYE

Download         Length: 267 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT275501 WP_047257105.1 NZ_CP120974:c3133598-3133374 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References