Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2876280..2876919 Replicon chromosome
Accession NZ_CP120974
Organism Moellerella wisconsensis strain XJ22MSE2

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag P8A16_RS12745 Protein ID WP_269430900.1
Coordinates 2876695..2876919 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag P8A16_RS12740 Protein ID WP_047256412.1
Coordinates 2876280..2876648 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A16_RS12715 2871481..2872242 - 762 WP_047256407.1 DNA polymerase III subunit epsilon -
P8A16_RS12720 2872299..2872766 + 468 WP_047256408.1 ribonuclease HI -
P8A16_RS12725 2872769..2873485 - 717 WP_047256409.1 methyltransferase domain-containing protein -
P8A16_RS12730 2873520..2874275 + 756 WP_047256410.1 hydroxyacylglutathione hydrolase -
P8A16_RS12735 2874347..2875702 + 1356 WP_047256411.1 murein transglycosylase D -
P8A16_RS12740 2876280..2876648 + 369 WP_047256412.1 Hha toxicity modulator TomB Antitoxin
P8A16_RS12745 2876695..2876919 + 225 WP_269430900.1 HHA domain-containing protein Toxin
P8A16_RS12755 2877666..2878127 - 462 WP_047256414.1 YbaY family lipoprotein -
P8A16_RS12760 2878522..2879385 + 864 WP_277850187.1 acyl-CoA thioesterase II -
P8A16_RS12765 2880450..2881733 - 1284 WP_047256416.1 ammonium transporter AmtB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(15-71)

Antitoxin

Biofilm formation regulator YbaJ

(1-117)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8977.32 Da        Isoelectric Point: 5.8622

>T275500 WP_269430900.1 NZ_CP120974:2876695-2876919 [Moellerella wisconsensis]
MNERQENMTKTDYLMRLRKCTTIETLERVIEKNKYELSDDELELFFSAADHRLAELTMNKLYDKIPASVWKYVR

Download         Length: 225 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14371.20 Da        Isoelectric Point: 4.5817

>AT275500 WP_047256412.1 NZ_CP120974:2876280-2876648 [Moellerella wisconsensis]
MDEYSPRYYDTAELKYLCDSLNNDAILSLHKTKTHWINDLSSQQSTNLNELIEHVAAFFWKFKIKYPSERLVISLVDEYL
DETYNLFGSPLITLNEFSDWQKMNTHLIDELNNDLKCSVAKL

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References