Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2470709..2471366 Replicon chromosome
Accession NZ_CP120974
Organism Moellerella wisconsensis strain XJ22MSE2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag P8A16_RS10995 Protein ID WP_047255277.1
Coordinates 2470709..2471119 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag P8A16_RS11000 Protein ID WP_047255278.1
Coordinates 2471100..2471366 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P8A16_RS10975 2465974..2467644 - 1671 WP_277850667.1 single-stranded-DNA-specific exonuclease RecJ -
P8A16_RS10980 2467716..2468408 - 693 WP_047255274.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
P8A16_RS10985 2468433..2469344 - 912 WP_047255275.1 site-specific tyrosine recombinase XerD -
P8A16_RS10990 2469565..2470083 + 519 WP_047255276.1 flavodoxin FldB -
P8A16_RS10995 2470709..2471119 - 411 WP_047255277.1 protein YgfX Toxin
P8A16_RS11000 2471100..2471366 - 267 WP_047255278.1 FAD assembly factor SdhE Antitoxin
P8A16_RS11005 2471627..2472619 + 993 WP_241500861.1 tRNA-modifying protein YgfZ -
P8A16_RS11010 2472637..2473257 + 621 WP_241500862.1 HD domain-containing protein -
P8A16_RS11015 2473429..2476308 - 2880 WP_047255281.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15525.49 Da        Isoelectric Point: 10.3270

>T275498 WP_047255277.1 NZ_CP120974:c2471119-2470709 [Moellerella wisconsensis]
VVLWKSNLSISWMAQLFSTCVHCVLGLVLLLAPWPTGNSIIWLPLLMVTIASWAKSQKNINKYKGIIVLTNGNKVQWKKN
EWSIITPPWCTRFGILLTLSALQGKPRKIKLWIAADAISEDDWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10681.11 Da        Isoelectric Point: 5.1391

>AT275498 WP_047255278.1 NZ_CP120974:c2471366-2471100 [Moellerella wisconsensis]
MDIDNKARIHWACRRGMRELDISIMPFFEHEYDGLNDNEKHQFIRLLECADPDLFNWLMNHGRPDDDELYHMIKLIQQRN
KDRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References