275494

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3133263..3133737 Replicon chromosome
Accession NZ_CP120970
Organism Moellerella wisconsensis strain XJ22MSE1

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag P6F44_RS13750 Protein ID WP_047257106.1
Coordinates 3133263..3133529 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag P6F44_RS13755 Protein ID WP_047257105.1
Coordinates 3133513..3133737 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P6F44_RS13730 3128583..3129497 - 915 WP_277850218.1 ribonuclease Z -
P6F44_RS13735 3129527..3131128 - 1602 WP_277850219.1 RNA repair transcriptional activator RtcR -
P6F44_RS13740 3131412..3131627 + 216 WP_047257108.1 hypothetical protein -
P6F44_RS13745 3131649..3132776 + 1128 WP_047257107.1 slipin family protein -
P6F44_RS13750 3133263..3133529 - 267 WP_047257106.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
P6F44_RS13755 3133513..3133737 - 225 WP_047257105.1 TraY domain-containing protein Antitoxin
P6F44_RS13760 3133927..3134055 + 129 WP_269430907.1 hypothetical protein -
P6F44_RS13770 3135542..3136318 - 777 WP_277850221.1 hypothetical protein -
P6F44_RS13775 3136521..3136739 - 219 WP_277850222.1 hypothetical protein -
P6F44_RS13780 3136977..3137753 - 777 WP_277850223.1 hypothetical protein -
P6F44_RS13785 3137734..3137907 - 174 WP_277850224.1 hypothetical protein -
P6F44_RS13790 3137956..3138138 - 183 WP_277850225.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 3134134..3134937 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-45)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10416.09 Da        Isoelectric Point: 9.5211

>T275494 WP_047257106.1 NZ_CP120970:c3133529-3133263 [Moellerella wisconsensis]
MVWTINYSERALKSLRKMDKQSARRIVDFMGLRIAALDDPRQLGKSLKGELGEFWRYRVGDYRILCEIRDDELVILAATI
GHRREIYE

Download         Length: 267 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8470.51 Da        Isoelectric Point: 4.5201

>AT275494 WP_047257105.1 NZ_CP120970:c3133737-3133513 [Moellerella wisconsensis]
MLAIRLSDDIETRLESLAKQTGRTKTFYAREAILTHLEDLEDYYLSAETIAKIRSGEELIHSSEEVRKTLGLDD

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References